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Tue Dec 13 2016 11:16:32 GMT+0100 (CET)2025-05-14 01:21:09

description

cell-division protein (septum formation), controls together with EzrA dynamics of the FtsZ ring

[SW|cell division] protein (septum formation), controls together with [[protein|EzrA]] dynamics of the [[protein|FtsZ]] ring

locus

BSU15150

BSU_15150

product

cell-division protein

[SW|cell division] protein, member of the [SW|divisome]

ec

outlinks

bsu

BSU15150

BSU_15150

[SW|Categories] containing this gene/protein

[SW|cell division], [SW|essential genes], [SW|membrane proteins]

Gene

Coordinates on the chromosome (coding sequence)

1,581,597 -> 1,581,950

The protein

Protein family

ftsL family (according to Swiss-Prot)

FtsL family (single member, according to UniProt)

The protein

Effectors of protein activity

degraded by [[protein|RasP]], stabilized against [[protein|RasP]] cleavage by [SW|DivIC] [Pubmed|20644139]

degraded by [[protein|RasP]], stabilized against [[protein|RasP]] cleavage by [[protein|DivIC]] [Pubmed|20644139]

The protein

[SW|Localization]

cell membrane (according to Swiss-Prot)

cell membrane (according to UniProt)

localizes to the division site, this depends on [[protein|FtsW]] [Pubmed|27895631]

The protein

[SW|Interactions]

[[protein|RasP]]-[[protein|FtsL]], [SW|DivIC]-[[protein|FtsL]] [Pubmed|10844672]

[[protein|PbpB]]-[SW|DivIB]-([[protein|FtsL]]-[SW|DivIC])2 [Pubmed|20870765], as part of the [SW|divisome]

[[protein|WalK]]-[[protein|FtsL]] [Pubmed|21219466]

Expression and Regulation

Operon

''[[protein|mraZ]]-[[protein|mraW]]-[[protein|ftsL]]-[[protein|pbpB]]'' [Pubmed|8636036,8244929]

Expression and Regulation

Regulation

constitutively expressed [Pubmed|23701187]

Biological materials

Mutant

MGNA-B127 (ylyB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1126 NBRP B. subtilis, Japan]

MGNA-B127 (ftsL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1126 NBRP B. subtilis, Japan]

References

Original Publications

9720875, 10792716, 16936019, 16549676, 17020588, 8636036, 10986263, 11994149, 10844672, 19429628, 20644139, 21219466, 23701187, 20870765

9720875, 10792716, 16936019, 16549676, 17020588, 8636036, 10986263, 11994149, 10844672, 19429628, 20644139, 21219466, 23701187, 20870765, 286740701, 29443967, 33077634

proteinLength

117

geneLength

354

Gene

Coordinates

1,581,597 1,581,950

The protein

Paralogous protein(s)

[[this]]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]