Mon Jan 02 2017 11:38:03 GMT+0100 (CET)2025-04-11 06:59:37

description

two-component system response regulator, controls gene expression in response to cell density (concentration of ComX)

two-component system response regulator, controls gene expression in response to cell density (concentration of [[protein|ComX]])

locus

BSU31680

BSU_31680

outlinks

bsu

BSU31680

BSU_31680

[SW|Categories] containing this gene/protein

[SW|genetic competence], [SW|transcription factors and their control], [SW|quorum sensing], [SW|phosphoproteins]

Gene

Coordinates on the chromosome (coding sequence)

3,252,804 -> 3,253,448

The protein

Protein family

ComA family (according to Swiss-Prot)

The protein

[SW|Interactions]

[[protein|RapC]]-[[protein|ComA]] [Pubmed|12950917]

[[protein|RapF]]-[[protein|ComA]] [Pubmed|15968044,22215984]

[[protein|RapH]]-[[protein|ComA]] [Pubmed|17581123]

[[protein|ComP]]-[[protein|ComA]]

[SW|ComA]-[SW|RpoA] [Pubmed|26582911]

[SW|ComA]-[SW|SigA] [Pubmed|26582911]

Expression and Regulation

Operon

''[[protein|comA]]-[[protein|yuxO]]'' [Pubmed|2507523]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigA]] [Pubmed|2507523]

References

Reviews

20030732, 12576575

20030732, 12576575, 30218468

References

Original Publications

17227471, 11133937, 2116363, 12067344, 8387999, 19202088, 10094672, 8643670, 11267663, 15968044, 16816200, 10447896, 12950917, 20302877, 12270822, 17581123, 16816200, 2507523, 20208433, 22215984, 24130811, 24425772, 24788106, 25598361, 25757097, 26582911, 26787913, 26927849, 28033323

17227471, 11133937, 2116363, 12067344, 8387999, 19202088, 10094672, 8643670, 11267663, 15968044, 16816200, 10447896, 12950917, 20302877, 12270822, 17581123, 2507523, 20208433, 22215984, 24130811, 24425772, 24788106, 25598361, 25757097, 26582911, 26787913, 26927849, 28033323

proteinLength

214

geneLength

645

Gene

Coordinates

3,252,804 3,253,448

The protein

Paralogous protein(s)

[[this]]

The protein

[SW|Domains]

[SW|Response regulatory domain] (aa 3-121) (according to UniProt)

[SW|HTH luxR-type domain] (aa 147-212) (according to UniProt)

The protein

additional information

information on binding sites can be found in the [http://www.prodoric2.de/detail.php?acc=MX000046 PRODORIC2 database]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

BKE31680 ([[gene|comA]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE31680 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTTTCCTCCCTTTTAC, downstream forward: _UP4_CTTTAAATGTTGGGGGGTGT

BKK31680 ([[gene|comA]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK31680 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTTTCCTCCCTTTTAC, downstream forward: _UP4_CTTTAAATGTTGGGGGGTGT