Tue Dec 13 2016 11:16:35 GMT+0100 (CET)2025-05-14 08:13:07
description
alkyl-sulphur catabolism regulator, transcriptional activator of the snaA-tcyJ-tcyK-tcyL-tcyM-tcyN-cmoO-cmoI-cmoJ-ribR-sndA-ytnM operon
alkyl-sulphur catabolism regulator, transcriptional activator of the [[gene|snaA]]-[[gene|tcyJ]]-[[gene|tcyK]]-[[gene|tcyL]]-[[gene|tcyM]]-[[gene|tcyN]]-[[gene|cmoO]]-[[gene|cmoI]]-[[gene|cmoJ]]-[[gene|ribR]]-[[gene|sndA]]-[[gene|ytnM ]]operon
locus
BSU29400
BSU_29400
product
alkyl-sulphur catabolism regulator, transcriptional activator (LysR family)
alkyl-sulphur catabolism regulator, transcriptional activator ([SW|LysR family])
ec
outlinks
bsu
BSU29400
BSU_29400
aminos
MELRSIKTFHTIVKFGSFYKAAEILNYSQPTISMRMKQLEQDLGVLLFERGKSLQLTKAGKLFYERTGDLLMQYEALKHNLSDLKEEEAGIINIGVSEPTASLIFPEILKDFLMDYPKITVNIKVDDANTCSQKLLDGTIDFAVCGEPELILENYYHPFFYDTLNVIVSDQHPLAEKKAVHLSDLAEERFIFTPANCPIRLQIEQHLHRELGNRYKKMELTSSMSHEYYVRENIGISIFTSTAHSKPFNGTKVIPILNLDITPPIGLLTNQKEVHFDRATKDLIARITKRFQQRSKELEGTSDKTITG
[SW|Categories] containing this gene/protein
[SW|biosynthesis/ acquisition of amino acids], [SW|sulfur metabolism], [SW|transcription factors and their control]
Gene
Coordinates on the chromosome (coding sequence)
3,008,938 -> 3,009,864
The protein
Protein family
[SW|LysR family]
[SW|LysR family] (according to UniProt)
Expression and Regulation
Operon
''ascR'' [Pubmed|9387221]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|16109943]
Expression and Regulation
Regulation
repressed in the presence of cysteine ([[protein|CymR]]) [Pubmed|16109943]
Expression and Regulation
Regulatory mechanism
[[protein|CymR]]: transcription repression [Pubmed|16109943]
proteinLength
308
geneLength
927
Gene
Coordinates
3,008,938 3,009,864
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Domains]
[SW|HTH lysR-type domain] (aa 1-57) (according to UniProt)
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
MGNA-A169 (ytlI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/169 NBRP B. subtilis, Japan]
BKE29400 ([[gene|ascR]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE29400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGTGCTCCCTCCTGTTT, downstream forward: _UP4_TAACTGAAAAAATAAAAACC
BKK29400 ([[gene|ascR]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK29400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGTGCTCCCTCCTGTTT, downstream forward: _UP4_TAACTGAAAAAATAAAAACC