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Fri Jan 29 2016 10:09:34 GMT+0100 (CET)2025-03-16 05:24:41

description

DNA polymerase III (gamma and tau subunits) part of the clamp-loader complex and the replisome

DNA polymerase III (gamma and tau subunits) part of the clamp-loader complex and the [SW|replisome]

locus

BSU00190

BSU_00190

function

DNA replication

[[category|DNA replication]]

outlinks

bsu

BSU00190

BSU_00190

[SW|Categories] containing this gene/protein

[SW|DNA replication], [SW|essential genes]

Gene

Coordinates on the chromosome (coding sequence)

26,814 -> 28,505

The protein

Catalyzed reaction/ biological activity

Deoxynucleoside triphosphate DNA(n) = diphosphate DNA(n1) (according to Swiss-Prot)

required for bacteriophage SPP1 replication [Pubmed|23268446]

deoxyribonucleoside 5'-triphosphate + DNA(n) --> diphosphate + DNA(n+1) (according to UniProt)

required for bacteriophage SPP1 replication [Pubmed|23268446]

The protein

Structure

[PDB|1JR3]

[PDB|1JR3] (from ''E. coli'', 39% identity) [Pubmed|11525729]

The protein

[SW|Interactions]

[[protein|DnaX]]-[[protein|DnaB]] [Pubmed|14757052]

[[protein|DnaX]]-[[protein|DnaC]] [Pubmed|23525462]

[[protein|DnaX]](3)-[[protein|HolA]]-[[protein|HolB]], the clamp-loader complex [Pubmed|23525462]

part of the [SW|replisome]: [[protein|PolC]]-[[protein|HolA]]-[[protein|HolB]]-[[protein|DnaX]]-[[protein|DnaN]]-[[protein|DnaG]]-[[protein|DnaC]]-[[protein|DnaI]]-[[protein|DnaD]]-[[protein|SsbA]]-[[protein|DnaE]]-[[protein|PriA]]-[[protein|DnaB]] [Pubmed|20122408]

References

16479537, 19415803, 14757052, 12974630, 1703271, 12466528, 20122408, 23525462, 23268446, 21958350

16479537, 19415803, 14757052, 12974630, 1703271, 12466528, 20122408, 23525462, 23268446, 21958350, 11525729, 30686488

proteinLength

563

geneLength

1692

Gene

Coordinates

26,814 28,505

The protein

Protein family

DnaX/STICHEL family (single member, according to UniProt)

The protein

Paralogous protein(s)

[[this]]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]