2019-06-06 11:12:352025-04-08 01:36:12
description
penicillin-binding protein 2C
class A penicillin-binding protein 2C
locus
BSU10110
BSU_10110
function
bifunctional glucosyltransferase/ transpeptidase
bifunctional glucosyltransferase/ transpeptidase, synthesis of spore peptidoglycan
outlinks
bsu
BSU10110
BSU_10110
The protein
[SW|Localization]
cell membrane, the major part is exposed to the outside (according to Swiss-Prot)
prespore [Pubmed|15758244]
during vegetative growth: septal, low flourescence at periphery [pubmed|14731276]
cell membrane, the major part is exposed to the outside (according to UniProt)
prespore [Pubmed|15758244]
during vegetative growth: septal, low flourescence at periphery [pubmed|14731276]
References
The protein
Catalyzed reaction/ biological activity
synthesis of spore peptidoglycan (with [[protein|PbpG]]) [pubmed|11567005]
[GlcNAc-(1→4)-Mur2Ac(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphospho-di-trans,octa-cis-undecaprenol + β-D-GlcNAc-(1→4)-Mur2Ac(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)-diphospho-di-trans,octa-cis-undecaprenol = [GlcNAc-(1→4)-Mur2Ac(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphospho-di-trans-octa-cis-undecaprenol + di-trans,octa-cis-undecaprenyl diphosphate + H+ (according to UniProt)
Preferential cleavage: (Ac)(2)-L-Lys-D-Ala-|-D-Ala. Also transpeptidation of peptidyl-alanyl moieties that are N-acyl substituents of D-alanine (according to UniProt)
The protein
Protein family
N-terminal part: [SW|glycosyltransferase 51 family] (according to UniProt)
C-terminal part: [SW|transpeptidase family] (according to UniProt)