Tue Feb 09 2016 20:32:27 GMT+0100 (CET)2025-05-26 02:33:22
locus
BSU28130
BSU_28130
outlinks
bsu
BSU28130
BSU_28130
[SW|Categories] containing this gene/protein
[SW|biosynthesis of cofactors], [SW|phosphoproteins]
Gene
Coordinates on the chromosome (coding sequence)
2,874,202 -> 2,875,176
The protein
Catalyzed reaction/ biological activity
2 5-aminolevulinate = porphobilinogen
2 5-aminolevulinate --> porphobilinogen + 2 H2O (according to UniProt)
The protein
Protein family
ALADH family (according to Swiss-Prot)
ALAD family (single member, according to UniProt)
The protein
Structure
[PDB|1W5Q] (from ''Pseudomonas aeruginosa'', 48% identity)
[PDB|1W5Q] (from ''Pseudomonas aeruginosa'', 48% identity) [Pubmed|15644204]
Expression and Regulation
Operon
''[[protein|hemA]]-[[protein|hemX]]-[[protein|hemC]]-[[protein|hemD]]-[[protein|hemB]]-[[protein|hemL]]'' [Pubmed|1672867]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|1672867]
Expression and Regulation
Regulation
induced by hydrogen peroxide ([[protein|PerR]]) [Pubmed|11532148]
Expression and Regulation
Regulatory mechanism
[[protein|PerR]]: transcription repression [Pubmed|11532148]
References
proteinLength
324
geneLength
975
Gene
Coordinates
2,874,202 2,875,176
The protein
Paralogous protein(s)
[[this]]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE28130 ([[gene|hemB]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE28130 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GCGGTGTCTATTAAATGATT, downstream forward: _UP4_TAATTTTATTCAGTTGACAG
BKK28130 ([[gene|hemB]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK28130 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GCGGTGTCTATTAAATGATT, downstream forward: _UP4_TAATTTTATTCAGTTGACAG
References
Reviews
References
Original Publications