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Sat Dec 26 2015 18:25:59 GMT+0100 (CET)2025-05-12 05:13:56

description

part of the flagellar type III export apparatus (flagellar Type III secretion system)

part of the flagellar type III export apparatus (flagellar Type III secretion system), part of the CORE complex required for flagellum and nanotube assembly

locus

BSU16380

BSU_16380

function

export of flagellum components

flagellum and nanotube assembly

product

part of the flagellar type III export apparatus

part of the type III CORE export apparatus

ec

outlinks

bsu

BSU16380

BSU_16380

[SW|Categories] containing this gene/protein

[SW|motility and chemotaxis], [SW|protein secretion], [SW|membrane proteins]

Gene

Coordinates on the chromosome (coding sequence)

1,706,599 -> 1,707,681

Gene

Phenotypes of a mutant

no secretion of [[protein|FlgM]], permanent inhibition of [[protein|SigD]] [Pubmed|25313396]

no secretion of [[protein|FlgM]], permanent inhibition of [[protein|SigD]] [Pubmed|25313396]

deficient in both nanotube production and the associated intercellular molecular trafficking [pubmed|30929979]

The protein

Protein family

type III secretion exporter family (according to Swiss-Prot)

Type III secretion exporter family (single member, according to UniProt)

The protein

[SW|Interactions]

[[protein|FlhA]]-[[protein|FlhB]] [Pubmed|22952860]

Expression and Regulation

Operon

part of the [[fla-che operon]]

''[[protein|flgB]]-[[protein|flgC]]-[[protein|fliE]]-[[protein|fliF]]-[[protein|fliG]]-[[protein|fliH]]-[[protein|fliI]]-[[protein|fliJ]]-[[protein|ylxF]]-[[protein|fliK]]-[[protein|flgD]]-[[protein|flgE]]-[[protein|fliL]]-[[protein|fliM]]-[[protein|fliY]]-[[protein|cheY]]-[[protein|fliZ]]-[[protein|fliP]]-[[protein|fliQ]]-[[protein|fliR]]-[[protein|flhB]]-[[protein|flhA]]-[[protein|flhF]]-[[protein|flhG]]-[[protein|cheB]]-[[protein|cheA]]-[[protein|cheW]]-[[protein|cheC]]-[[protein|cheD]]-[[protein|sigD]]-[[protein|swrB]]'' [Pubmed|9657996,8157612,15175317]

''[[protein|ylxF]]-[[protein|fliK]]-[[protein|flgD]]-[[protein|flgE]]-[[protein|fliL]]-[[protein|fliM]]-[[protein|fliY]]-[[protein|cheY]]-[[protein|fliZ]]-[[protein|fliP]]-[[protein|fliQ]]-[[protein|fliR]]-[[protein|flhB]]-[[protein|flhA]]-[[protein|flhF]]-[[protein|flhG]]-[[protein|cheB]]-[[protein|cheA]]-[[protein|cheW]]-[[protein|cheC]]-[[protein|cheD]]-[[protein|sigD]]-[[protein|swrB]]'' [Pubmed|20233303]

Expression and Regulation

[SW|Sigma factor]

''[[protein|flgB]]'': [[protein|SigA]] [Pubmed|9657996], [[protein|SigD]] [Pubmed|9657996]

''[[protein|ylxF]]'': [[protein|SigD]] [Pubmed|20233303]

Expression and Regulation

Regulation

see [[fla-che operon]]

Expression and Regulation

Regulatory mechanism

see [[fla-che operon]]

References

Reviews

24064315, 18931786

26490009

24064315, 18931786, 26490009

References

Original publications

8299954, 17850253, 14651647, 9657996, 8157612, 15175317, 25313396, 24386445, 22952860

8299954, 17850253, 14651647, 9657996, 8157612, 15175317, 25313396, 24386445, 22952860, 30929979, 32157081

proteinLength

360

geneLength

1083

Gene

Coordinates

1,706,599 1,707,681

The protein

Paralogous protein(s)

[[this]]

The protein

Structure

[PDB|6S3L] (from Vibrio mimicus, 37% identity) [pubmed|32157081]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

BKE16380 ([[gene|flhB]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE16380 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CTGCAGGTCAACTCTAAGCT, downstream forward: _UP4_TGAATTTTTCGATTTAAAAG

BKK16380 ([[gene|flhB]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK16380 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CTGCAGGTCAACTCTAAGCT, downstream forward: _UP4_TGAATTTTTCGATTTAAAAG