Sat Dec 26 2015 18:25:59 GMT+0100 (CET)2025-05-12 05:13:56
description
part of the flagellar type III export apparatus (flagellar Type III secretion system)
part of the flagellar type III export apparatus (flagellar Type III secretion system), part of the CORE complex required for flagellum and nanotube assembly
locus
BSU16380
BSU_16380
function
export of flagellum components
flagellum and nanotube assembly
product
part of the flagellar type III export apparatus
part of the type III CORE export apparatus
ec
outlinks
bsu
BSU16380
BSU_16380
[SW|Categories] containing this gene/protein
[SW|motility and chemotaxis], [SW|protein secretion], [SW|membrane proteins]
Gene
Coordinates on the chromosome (coding sequence)
1,706,599 -> 1,707,681
Gene
Phenotypes of a mutant
no secretion of [[protein|FlgM]], permanent inhibition of [[protein|SigD]] [Pubmed|25313396]
no secretion of [[protein|FlgM]], permanent inhibition of [[protein|SigD]] [Pubmed|25313396]
deficient in both nanotube production and the associated intercellular molecular trafficking [pubmed|30929979]
The protein
Protein family
type III secretion exporter family (according to Swiss-Prot)
Type III secretion exporter family (single member, according to UniProt)
The protein
[SW|Interactions]
[[protein|FlhA]]-[[protein|FlhB]] [Pubmed|22952860]
Expression and Regulation
Operon
part of the [[fla-che operon]]
''[[protein|flgB]]-[[protein|flgC]]-[[protein|fliE]]-[[protein|fliF]]-[[protein|fliG]]-[[protein|fliH]]-[[protein|fliI]]-[[protein|fliJ]]-[[protein|ylxF]]-[[protein|fliK]]-[[protein|flgD]]-[[protein|flgE]]-[[protein|fliL]]-[[protein|fliM]]-[[protein|fliY]]-[[protein|cheY]]-[[protein|fliZ]]-[[protein|fliP]]-[[protein|fliQ]]-[[protein|fliR]]-[[protein|flhB]]-[[protein|flhA]]-[[protein|flhF]]-[[protein|flhG]]-[[protein|cheB]]-[[protein|cheA]]-[[protein|cheW]]-[[protein|cheC]]-[[protein|cheD]]-[[protein|sigD]]-[[protein|swrB]]'' [Pubmed|9657996,8157612,15175317]
''[[protein|ylxF]]-[[protein|fliK]]-[[protein|flgD]]-[[protein|flgE]]-[[protein|fliL]]-[[protein|fliM]]-[[protein|fliY]]-[[protein|cheY]]-[[protein|fliZ]]-[[protein|fliP]]-[[protein|fliQ]]-[[protein|fliR]]-[[protein|flhB]]-[[protein|flhA]]-[[protein|flhF]]-[[protein|flhG]]-[[protein|cheB]]-[[protein|cheA]]-[[protein|cheW]]-[[protein|cheC]]-[[protein|cheD]]-[[protein|sigD]]-[[protein|swrB]]'' [Pubmed|20233303]
Expression and Regulation
[SW|Sigma factor]
''[[protein|flgB]]'': [[protein|SigA]] [Pubmed|9657996], [[protein|SigD]] [Pubmed|9657996]
''[[protein|ylxF]]'': [[protein|SigD]] [Pubmed|20233303]
Expression and Regulation
Regulation
see [[fla-che operon]]
Expression and Regulation
Regulatory mechanism
see [[fla-che operon]]
References
Reviews
References
Original publications
proteinLength
360
geneLength
1083
Gene
Coordinates
1,706,599 1,707,681
The protein
Paralogous protein(s)
[[this]]
The protein
Structure
[PDB|6S3L] (from Vibrio mimicus, 37% identity) [pubmed|32157081]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE16380 ([[gene|flhB]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE16380 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CTGCAGGTCAACTCTAAGCT, downstream forward: _UP4_TGAATTTTTCGATTTAAAAG
BKK16380 ([[gene|flhB]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK16380 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CTGCAGGTCAACTCTAAGCT, downstream forward: _UP4_TGAATTTTTCGATTTAAAAG