SubtiBank SubtiBank
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Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)2025-05-12 16:33:26

description

cell division protein, membrane anchor for FtsZ

cell division protein, membrane anchor for [[protein|FtsZ]]

locus

BSU15280

BSU_15280

product

cell division protein

[SW|cell division] protein, member of the [SW|divisome]

ec

outlinks

subtilist

gene_detail+BG10231

gene_detail BG10231

outlinks

bsu

BSU15280

BSU_15280

syns

spoIIN

[SW|Categories] containing this gene/protein

[SW|cell division], [SW|membrane proteins]

Gene

Phenotypes of a mutant

cells become elongated [Pubmed|24218584]

the ''[[protein|ftsA]]'' mutation is synthetically lethal with a ''[[protein|sepF]]'' mutation [Pubmed|24218584]

cells become elongated [Pubmed|24218584]

the ''[[gene|ftsA]]'' mutation is synthetically lethal with a ''[[gene|sepF]]'' mutation [Pubmed|24218584]

The protein

Protein family

ftsA/mreB family (according to Swiss-Prot)

[SW|FtsA/MreB family] (according to UniProt)

The protein

[SW|Localization]

septal at the cell membrane [Pubmed|20566861]

septal localization depends on the proton motive force [Pubmed|20566861]

septal at the cell membrane (35% of the molecules) [Pubmed|29439991,20566861]

cytoplasma (65% of the molecules) [pubmed|29439991]

septal localization depends on the proton motive force [Pubmed|20566861]

The protein

[SW|Interactions]

[[protein|FtsZ]]-[[protein|FtsA]] [Pubmed|16159787]

[[protein|PlsX]]-[[protein|FtsA]] [Pubmed|24224907]

Expression and Regulation

Operon

''[[protein|ftsA]]-[[protein|ftsZ]]'' [Pubmed|1569582]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigA]] [Pubmed|1569582], [[protein|SigH]] [Pubmed|1569582]

Expression and Regulation

Regulation

activated by [[protein|WalR]] [Pubmed|10878122]

References

Reviews

19680248

19680248, 28254403

References

Original Publications

16796675, 12081956, 16159787, 11298280, 18776011, 9287012, 1569582, 10878122, 7592498, 20566861, 23036588, 23701187, 24218584, 24224907, 24316672

29439991, 16796675, 12081956, 16159787, 11298280, 18776011, 9287012, 1569582, 10878122, 7592498, 20566861, 23036588, 23701187, 24218584, 24224907, 24316672, 28189581, 24746687

proteinLength

440

geneLength

1323

Gene

Coordinates

1,596,474 1,597,796

The protein

Catalyzed reaction/ biological activity

required for septum recruitment of [[protein|SftA]] [pubmed|29439991]

The protein

Paralogous protein(s)

[[this]]

The protein

Structure

[PDB|3WQT] (from Staphylococcus aureus, 31% identity) [pubmed|24746687]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]