SubtiBank SubtiBank
Version comparison:

2017-8-11 16:0:32025-05-09 11:45:04

description

two-component response regulator (OmpR family), regulation of phosphate metabolism

two-component response regulator ([SW|OmpR family]), regulation of phosphate metabolism

locus

BSU29110

BSU_29110

geneLength

720

723

function

regulation of phosphate metabolism (phoA, phoB, phoD, resA | resABCDE, tagA-tagB, tagD | tagDEF, tuaA | tuaA-H)

regulation of phosphate metabolism ([[gene|phoA]], [[gene|phoB]], [[gene|phoD]], [[gene|resA|resABCDE]], [[gene|tagA]]-[[gene|tagB]], [[gene|tagD|tagDEF]], [[gene|tuaA|tuaA-H]])

product

two-component response regulator (OmpR family)

two-component response regulator ([SW|OmpR family])

ec

outlinks

bsu

BSU29110

BSU_29110

Gene

Coordinates

2,977,800 → 2,978,522

2,977,800 2,978,522

The protein

Structure

[PDB|1MVO] (receiver domain)

[PDB|2OQR] (from Mycobacterium tuberculosis, 44% identity) [pubmed|17942407]

[PDB|1MVO] (receiver domain)

The protein

[SW|Localization]

cell membrane (according to Swiss-Prot)

cytoplasm (according to UniProt)

Biological materials

Mutant

1A966 ( ''phoP''::''tet''), [Pubmed|14973033], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A966&Search=1A966 BGSC]

1A966 ( ''phoP''::''tet''), [Pubmed|14973033], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A966&Search=1A966 BGSC]

BKE29110 ([[gene|phoP]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE29110 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCTGTGCCTCCAGTATT, downstream forward: _UP4_TATAAACTGGAGGAGCCAAA

BKK29110 ([[gene|phoP]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK29110 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCTGTGCCTCCAGTATT, downstream forward: _UP4_TATAAACTGGAGGAGCCAAA

Labs working on this gene/protein

[SW|Marion Hulett], University of Illinois at Chicago, USA [http://www.uic.edu/depts/bios/faculty/hulett/hulettm.shtml Homepage]

References

Regulation of ''[[gene|phoP]]]-[[phoR]'' expression

20382764, 14762014, 12850135, 15205429, 16452408, 25666134

References

Biochemical analyses

9680208, 9611818, 12486063, 20167622, 10433720, 17085571, 14973033, 12486062

9680208, 9611818, 12486063, 20167622, 10433720, 17085571, 14973033, 12486062, 17942407

References

Targets of PhoR==

Additional publications:''' [Pubmed|21636651]

20059685 16030210, 10913081, 10094677, 9683503, 9988472, 9457886, 9335276, 9593301, 9098050,

Other original publications

10094672, 15576792

The protein

Paralogous protein(s)

[[this]]

The protein

[SW|Domains]

[SW|Response regulatory domain] (aa 4-118) (according to UniProt)

The protein

additional information

information on binding sites can be found in the [http://www.prodoric2.de/detail.php?acc=MX000057 PRODORIC2 database]

labs

[SW|Marion Hulett], University of Illinois at Chicago, USA [http://www.uic.edu/depts/bios/faculty/hulett/hulettm.shtml Homepage]

References

Reviews

30459743

References

Regulation of [[gene|phoP]]-[[gene|phoR]] expression

20382764, 14762014, 12850135, 15205429, 16452408, 25666134

References

Targets of PhoR

20059685 16030210, 10913081, 10094677, 9683503, 9988472, 9457886, 9335276, 9593301, 9098050, 21636651

References

Other original publications

10094672, 15576792