SubtiBank SubtiBank
Version comparison:

Tue Dec 13 2016 11:16:34 GMT+0100 (CET)2025-05-14 09:04:21

description

probable transcription termination

transcription antitermination factor

locus

BSU24320

BSU_24320

function

unknown

stable RNA transcription

product

unknown

antitermination factor

ec

outlinks

bsu

BSU24320

BSU_24320

aminos

MKRRTAREKALQALFQIDVSDIAVNEAIEHALDEEKTDPFFEQLVHGVLEHQDQLDEMISKHLVNWKLDRIANVDRAILRLAAYEMAYAEDIPVNVSMNEAIELAKRFGDDKATKFVNGVLSNIKSDIEQS

[SW|Categories] containing this gene/protein

[SW|transcription]

Gene

Coordinates on the chromosome (coding sequence)

2,529,267 -> 2,529,662

The protein

Protein family

nusB family (according to Swiss-Prot)

nusB family (single member, according to UniProt)

Expression and Regulation

Operon

''[[protein|nusB]]-[[protein|folD]]'' [Pubmed|2536750,11591660]

Expression and Regulation

Regulation

repressed in the presence of purine nucleotides ([[protein|PurR]]) [Pubmed|2536750,11591660]

[[protein|RelA]] dependent downregulation (Class I) during stringent response [Pubmed|11948165]

Expression and Regulation

Regulatory mechanism

[[protein|PurR]]: transcription repression (molecular inducer: PRPP) [Pubmed|2536750,11591660]

References

11948165, 16707701, 11591660, 2536750

11948165, 16707701, 11591660, 2536750, 10881194, 21652641, 30023707

proteinLength

131

geneLength

396

Gene

Coordinates

2,529,267 2,529,662

The protein

Paralogous protein(s)

[[this]]

The protein

Structure

[PDB|1EYV] (from Mycobacterium tuberculosis, 40% identity) [pubmed|10881194]

[PDB|3R2C] (the [[protein|NusB]]-[[protein|RpsJ]] complex from Aquifex aeolicus) [pubmed|21652641]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

MGNA-C368 (yqhZ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2366 NBRP B. subtilis, Japan]

BKE24320 ([[gene|nusB]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE24320 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTCTTTCTCCTTTGAT, downstream forward: _UP4_TAGGAGGAAAGAAAATGACT

BKK24320 ([[gene|nusB]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK24320 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTCTTTCTCCTTTGAT, downstream forward: _UP4_TAGGAGGAAAGAAAATGACT