Tue Dec 13 2016 11:16:36 GMT+0100 (CET)2025-05-09 06:47:12
locus
BSU34030
BSU_34030
ec
outlinks
bsu
BSU34030
BSU_34030
aminos
MTKGTIQNQESFLNRIASSLGRERRTGGVAVPEWAHQPQYKTLEGYSADDLVTVLKNHCVKIHTELIETDSTGLYDALREQVSRFSGGPVIIPKDPRFEEYGLKSLLTKDWPSEGTPVWEWDADKGEENIKKAEQANVGITFSEITLAESGTVVLFSSKDIGRSVSLLPTTYIAIVPKSSIVPRMTQASDIIRQNIANGVTVPSCINYITGPSNSADIEMDLVVGVHGPVKAAYILVSDR
[SW|Categories] containing this gene/protein
[SW|utilization of specific carbon sources], [SW|phosphoproteins]
Gene
Coordinates on the chromosome (coding sequence)
3,492,797 -> 3,493,519
The protein
Protein family
UPF0707 family (according to Swiss-Prot)
LutC/YkgG family (single member, according to UniProt)
Expression and Regulation
Operon
''[[protein|lutA]]-[[protein|lutB]]-[[protein|lutC]]'' [Pubmed|19201793]
Expression and Regulation
Regulation
induction by lactate [Pubmed|19201793]
repressed by [[protein|SinR]] [Pubmed|19201793]
part of the iron sparing response, down-regulation in a'' [[protein|fur]]'' mutant ([[protein|Fur]], [[protein|FsrA]], [[protein|FpbB]]) [Pubmed|22427629]
Expression and Regulation
Regulatory mechanism
dual repression by [[protein|LutR]] (inducer lactate) and [[protein|SinR]] [Pubmed|19201793]
[[protein|SinR]]: transcription repression [Pubmed|19201793]
[[protein|FsrA]]: translational repression [Pubmed|22427629]
[[protein|FbpB]]: acts as RNA chaperone, increases interaction between ''[[protein|fsrA]]'' and ''[[protein|lutA]]-[[protein|lutB]]-[[protein|lutC]]'' RNAs [Pubmed|22427629]
Labs working on this gene/protein
[SW|Richard Losick], Harvard Univ., Cambridge, USA [http://www.mcb.harvard.edu/Losick/ homepage]
proteinLength
240
geneLength
723
Gene
Coordinates
3,492,797 3,493,519
The protein
Paralogous protein(s)
[[this]]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
MGNA-A470 (yvbY::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/470 NBRP B. subtilis, Japan]
BKE34030 ([[gene|lutC]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE34030 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATTCTGAATGGTTCCCTTCG, downstream forward: _UP4_TGAACTCAGGAAGCCCGGCA
BKK34030 ([[gene|lutC]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK34030 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATTCTGAATGGTTCCCTTCG, downstream forward: _UP4_TGAACTCAGGAAGCCCGGCA
labs
[SW|Richard Losick], Harvard Univ., Cambridge, USA [http://www.mcb.harvard.edu/Losick/ homepage]