Thu Aug 18 2016 18:38:27 GMT+0200 (CEST)2025-05-31 12:39:33
locus
BSU15210
BSU_15210
ec
outlinks
bsu
BSU15210
BSU_15210
[SW|Categories] containing this gene/protein
[SW|cell wall synthesis], [SW|biosynthesis of cell wall components], [SW|sporulation proteins], [SW|membrane proteins]
Gene
Coordinates on the chromosome (coding sequence)
1,590,317 -> 1,591,417
The protein
Protein family
ftsW/rodA/spoVE family (according to Swiss-Prot) SEDS proteins (shape, elongation, division, and sporulation)
[SW|SEDS proteins] (shape, elongation, division, and sporulation) [Pubmed|27525505]
SEDS family (with [[protein|FtsW]] and [[protein|RodA]], according to UniProt)
The protein
Paralogous protein(s)
[[protein|FtsW]], [[protein|RodA]]
[[this]]
The protein
[SW|Interactions]
[SW|SpoVD]-[SW|SpoVE] [Pubmed|20417640], this protects [SW|SpoVE] from proteolytic degradation [Pubmed|20417640]
Expression and Regulation
Operon
''[[protein|murE]]-[[protein|mraY]]-[[protein|murD]]-[SW|spoVE]-[[protein|murG]]-[[protein|murB]]-[SW|divIB]-[[protein|ylxW]]-[[protein|ylxX]]-[[protein|sbp]]'' [Pubmed|1391053]
''[SW|spoVE]-[[protein|murG]]-[[protein|murB]]-[SW|divIB]-[[protein|ylxW]]-[[protein|ylxX]]-[[protein|sbp]]'' [Pubmed|1391053]
''[SW|spoVE]'' [Pubmed|1391053]
Expression and Regulation
[SW|Sigma factor]
''[SW|spoVE]'': [[protein|SigE]] [Pubmed|8320223]
Expression and Regulation
Regulation
expressed during vegatative growth, then switched off, and again expressed during sporulation in the mother cell ([[protein|SigE]]) [Pubmed|1391053]
Expression and Regulation
Regulatory mechanism
[SW|SpoIIID]: transcription repression [Pubmed|15383836]
Expression and Regulation
Additional information
the mRNA is cleaved by [[rnc|RNase III]] [PubMed|26883633]
the mRNA is cleaved by [[protein|Rnc|RNase III]] [PubMed|26883633]
References
proteinLength
366
geneLength
1101
Gene
Coordinates
1,590,317 1,591,417
The protein
Structure
[PDB|6BAR] (from Thermus thermophilus,corresponds to aa 99... 357, 38% identity) [pubmed|29590088]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE15210 ([[gene|spoVE]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE15210 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAGCAATCGACACCCCAA, downstream forward: _UP4_TAACGAATGTATTTCCAAGC
BKK15210 ([[gene|spoVE]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK15210 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAGCAATCGACACCCCAA, downstream forward: _UP4_TAACGAATGTATTTCCAAGC