SubtiBank SubtiBank
Version comparison:

2019-06-26 11:22:25Mon Aug 31 2015 13:53:37 GMT+0200 (CEST)

proteinLength

413

geneLength

1242

Gene

Coordinates

1,209,183 1,210,424

The protein

Catalyzed reaction/ biological activity

(Z)-hexadec-11-enoyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-carrier-protein] + CO2 + [acyl-carrier-protein] (according to Swiss-Prot)

[[protein|SigW]]-dependent expression of ''[[gene|fabF]]'' and the ''[[gene|yuaF]]-[[gene|floT]]-[[gene|yuaI]]'' operon result in reduced membrane fluidity [Pubmed|21542858,22178969]

(Z)-hexadec-11-enoyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-carrier-protein] + CO2 + [acyl-carrier-protein] (according to Swiss-Prot)

[[protein|SigW]]-dependent expression of ''[[protein|fabF]]'' and the ''[[protein|yuaF]]-[[protein|floT]]-[[protein|yuaI]]'' operon result in reduced membrane fluidity [Pubmed|21542858,22178969]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

syns

yjaY

[SW|Categories] containing this gene/protein

[SW|membrane dynamics], [SW|biosynthesis of lipids], [SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)], [SW|essential genes]

Expression and Regulation

Operon

''[SW|fabHA]-[[protein|fabF]]'' [Pubmed|12737802]

Expression and Regulation

[SW|Sigma factor]

''[SW|fabHA]'': [[protein|SigA]] [Pubmed|12737802]

''[[protein|fabF]]'': [[protein|SigW]] [Pubmed|21542858]

Expression and Regulation

Regulation

''[SW|fabHA]'': expressed when the cells experience a lack of malonyl-CoA ([[protein|FapR]]) [Pubmed|12737802]

''[SW|fabHA]'': induced upon fatty acid biosynthesis inhibition [Pubmed|21383089]

''[[protein|fabF]]'': induced by alkaline shock and by polymyxin B, vancomycin, cephalosporin C, D-cycloserine, and triton X-100 ([[protein|SigW]]) [Pubmed|21542858]

Expression and Regulation

Regulatory mechanism

[[protein|FapR]]: transcription repression [Pubmed|12737802]