2019-06-26 11:22:25Mon Aug 31 2015 13:53:37 GMT+0200 (CEST)
proteinLength
413
geneLength
1242
Gene
Coordinates
1,209,183 1,210,424
The protein
Catalyzed reaction/ biological activity
(Z)-hexadec-11-enoyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-carrier-protein] + CO2 + [acyl-carrier-protein] (according to Swiss-Prot)
[[protein|SigW]]-dependent expression of ''[[gene|fabF]]'' and the ''[[gene|yuaF]]-[[gene|floT]]-[[gene|yuaI]]'' operon result in reduced membrane fluidity [Pubmed|21542858,22178969]
(Z)-hexadec-11-enoyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-carrier-protein] + CO2 + [acyl-carrier-protein] (according to Swiss-Prot)
[[protein|SigW]]-dependent expression of ''[[protein|fabF]]'' and the ''[[protein|yuaF]]-[[protein|floT]]-[[protein|yuaI]]'' operon result in reduced membrane fluidity [Pubmed|21542858,22178969]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
syns
yjaY
[SW|Categories] containing this gene/protein
[SW|membrane dynamics], [SW|biosynthesis of lipids], [SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)], [SW|essential genes]
Expression and Regulation
Operon
''[SW|fabHA]-[[protein|fabF]]'' [Pubmed|12737802]
Expression and Regulation
[SW|Sigma factor]
''[SW|fabHA]'': [[protein|SigA]] [Pubmed|12737802]
''[[protein|fabF]]'': [[protein|SigW]] [Pubmed|21542858]
Expression and Regulation
Regulation
''[SW|fabHA]'': expressed when the cells experience a lack of malonyl-CoA ([[protein|FapR]]) [Pubmed|12737802]
''[SW|fabHA]'': induced upon fatty acid biosynthesis inhibition [Pubmed|21383089]
''[[protein|fabF]]'': induced by alkaline shock and by polymyxin B, vancomycin, cephalosporin C, D-cycloserine, and triton X-100 ([[protein|SigW]]) [Pubmed|21542858]
Expression and Regulation
Regulatory mechanism
[[protein|FapR]]: transcription repression [Pubmed|12737802]