SubtiBank SubtiBank
Version comparison:

2017-04-10 11:53:432025-05-16 04:51:16

description

ATPase, centromere-like function involved in forespore chromosome partitioning / negative regulation of sporulation initiation

ATPase, centromere-like function involved in forespore chromosome partitioning / negative regulation of [[category|Sporulation]] initiation

locus

BSU40970

BSU_40970

geneLength

759

762

function

forespore chromosome partitioning /
negative regulation of sporulation initiation

forespore chromosome partitioning / negative regulation of [[category|Sporulation]] initiation

product

negative regulator of sporulation initiation

negative regulator of [[category|Sporulation]] initiation

outlinks

bsu

BSU40970

BSU_40970

Gene

Coordinates

4,206,397 -> 4,207,158

4,206,397 4,207,158

The protein

Catalyzed reaction/ biological activity

regulates [SW|DNA replication] initiation by either inhibiting or activating the [SW|DNA replication] initiator protein [[protein|DnaA]] [Pubmed|21235642]; regulation of ''Spo0A'' expression [Pubmed|10852876]

regulates [SW|DNA replication] initiation by either inhibiting or activating the [SW|DNA replication] initiator protein [[protein|DnaA]] [Pubmed|21235642]; regulation of ''Spo0A'' expression [Pubmed|10852876]

ATP + H2O --> ADP + H+ + phosphate (according to UniProt)

The protein

Protein family

parA family (according to Swiss-Prot)

ParA family (with [[protein|FlhG]] and [[protein|MinD]], according to UniProt)

Labs working on this gene/protein

[SW|Heath Murray], Centre for Bacterial Cell Biology, Newcastle, UK [http://www.ncl.ac.uk/camb/staff/profile/heath.murray homepage]

References

Reviews

20157337, 22934648, 26286503, 26706151, 28075389

20157337, 22934648, 26286503, 26706151, 28075389, 30863373

References

Original publications

15659156, 11532141, 19450516, 18854156, 10619015, 8866474, 12492861, 9701805, 12950914, 14651647, 19450516, 20566861, 21235642, 10852876, 14563866, 26253537, 22286949, 21911367, 27059541, 27489185

15659156, 11532141, 19450516, 18854156, 10619015, 8866474, 12492861, 9701805, 12950914, 14651647, 19450516, 20566861, 21235642, 10852876, 14563866, 26253537, 22286949, 21911367, 27059541, 27489185, 28373206, 27489185, 31318889

Gene

Phenotypes of a mutant

defective in oriC segregation during [[category|Sporulation]] [pubmed|27489185]

The protein

Paralogous protein(s)

[[this]]

The protein

Structure

[PDB|5U1G] [pubmed|28373206]

[PDB|5U1J] [pubmed|28373206]

Biological materials

Mutant

BKE40970 ([[gene|parA]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE40970 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGATGTCACCTACTTTCA, downstream forward: _UP4_GATTTAGCAAAGGAAGTGGC

BKK40970 ([[gene|parA]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK40970 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGATGTCACCTACTTTCA, downstream forward: _UP4_GATTTAGCAAAGGAAGTGGC

labs

[SW|Heath Murray], Centre for Bacterial Cell Biology, Newcastle, UK [http://www.ncl.ac.uk/camb/staff/profile/heath.murray homepage]