Mon Aug 31 2015 13:52:36 GMT+0200 (CEST)2025-05-30 02:08:32
description
Anti-protein serine kinase, phosphorylates RsbV
anti-[SW|sigma factor] to [[protein|SigB]], protein serine kinase, phosphorylates [[protein|RsbV]]
locus
BSU04720
BSU_04720
function
control of SigB activity
control of [[protein|SigB ]]activity
product
anti-protein serine kinase
anti-[SW|sigma factor], protein serine kinase
ec
outlinks
bsu
BSU04720
BSU_04720
[SW|Categories] containing this gene/protein
[SW|protein modification], [SW|sigma factors and their control], [SW|general stress proteins (controlled by SigB)]
Gene
Coordinates on the chromosome (coding sequence)
522,414 -> 522,896
The protein
Catalyzed reaction/ biological activity
ATP
phosphorylation of [[protein|RsbV]]
negative regulator (by binding) of [[protein|SigB]]
ATP + L-seryl-[protein] --> ADP + H+ + O-phospho-L-seryl-[protein] (according to UniProt)
ATP + L-threonyl-[protein] --> ADP + H+ + O-phospho-L-threonyl-[protein] (according to UniProt)
The protein
Protein family
anti-sigma-factor family (according to Swiss-Prot)
anti-sigma-factor family (with [[protein|SpoIIAB]], according to UniProt)
The protein
[SW|Interactions]
[[protein|RsbV]]-[[protein|RsbW]] [Pubmed|8144446]
[[protein|SigB]]-[[protein|RsbW]] [Pubmed|12270815]
Expression and Regulation
Operon
''[[protein|rsbR]]-[[protein|rsbS]]-[[protein|rsbT]]-[[protein|rsbU]]-[[protein|rsbV]]-[[protein|rsbW]]-[[protein|sigB]]-[[protein|rsbX]]'' [Pubmed|8002610]
''[[protein|rsbV]]-[[protein|rsbW]]-[[protein|sigB]]-[[protein|rsbX]]'' [Pubmed|2170324]
Expression and Regulation
[SW|Sigma factor]
''[[protein|rsbR]]'': [[protein|SigA]] [Pubmed|8002610]
''[[protein|rsbV]]:'' [[protein|SigB]] [Pubmed|11544224]
Expression and Regulation
Regulation
''[[protein|rsbV]]:'' induced by stress ([[protein|SigB]]) [Pubmed|11544224]
Labs working on this gene/protein
[SW|Bill Haldenwang], San Antonio, USA
[SW|Chet Price], Davis, USA [http://foodscience.ucdavis.edu/price_lab/pricelab.html homepage]
References
proteinLength
160
geneLength
483
Gene
Coordinates
522,414 522,896
The protein
Paralogous protein(s)
[[this]]
The protein
Structure
[PDB|1TIL] ([[protein|SpoIIAB]], 32% identity) [pubmed|15236958]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE04720 ([[gene|rsbW]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE04720 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTCGATGTAATCAGCATTAT, downstream forward: _UP4_TATTTAAATGGGGAGCGAGT
BKK04720 ([[gene|rsbW]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK04720 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTCGATGTAATCAGCATTAT, downstream forward: _UP4_TATTTAAATGGGGAGCGAGT
labs
[SW|Bill Haldenwang], San Antonio, USA
[SW|Chet Price], Davis, USA [http://foodscience.ucdavis.edu/price_lab/pricelab.html homepage]
References
Reviews
References
Original publications