SubtiBank SubtiBank
Version comparison:

Tue Dec 13 2016 11:16:35 GMT+0100 (CET)2025-05-27 21:37:31

locus

BSU30500

BSU_30500

ec

outlinks

bsu

BSU30500

BSU_30500

aminos

[SW|Categories] containing this gene/protein

[SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)]

Gene

Coordinates on the chromosome (coding sequence)

3,121,538 -> 3,122,641

Gene

Phenotypes of a mutant

increased sensitivity to bacitracin, due to the accumulation of heptaprenyl pyrophosphate [Pubmed|24806199]

sensitivity is increased in a ''[[protein|ytpB]] [[protein|menA]]'' double mutant [Pubmed|24806199]

increased sensitivity to bacitracin, due to the accumulation of heptaprenyl pyrophosphate [Pubmed|24806199]

sensitivity is increased in a ''[[gene|ytpB]] [[gene|menA]]'' double mutant [Pubmed|24806199]

Expression and Regulation

Operon

''[[protein|ytpA]]-[[protein|ytpB]]'' [Pubmed|18179421]

''[[protein|ytpB]]'' [Pubmed|9387221]

Expression and Regulation

[SW|Sigma factor]

''[[protein|ytpA]]'': [[protein|SigM]] [http://www.ncbi.nlm.nih.gov/sites/entrez/18179421 Pubmed]

Expression and Regulation

Regulation

expressed under conditions of salt stress ([[protein|SigM]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/18179421 Pubmed]

proteinLength

367

geneLength

1104

Gene

Coordinates

3,121,538 3,122,641

The protein

Catalyzed reaction/ biological activity

all-trans-heptaprenyl diphosphate --> diphosphate + tetraprenyl-β-curcumene (according to UniProt)

The protein

Paralogous protein(s)

[[this]]

The protein

Structure

[PDB|5YO8] (from Bacillus alcalophilus, 50% identity)

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

MGNA-A164 (ytpB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/164 NBRP B. subtilis, Japan]

BKE30500 ([[gene|ytpB]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE30500 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAACACATGCACCCCCTACT, downstream forward: _UP4_AAAAATTCAAAGAAAAAAGC

BKK30500 ([[gene|ytpB]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK30500 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAACACATGCACCCCCTACT, downstream forward: _UP4_AAAAATTCAAAGAAAAAAGC