2019-09-14 16:31:482025-05-23 13:48:39
product
high-affinity potassium transporter
high-affinity K+/H+ symporter
The protein
Catalyzed reaction/ biological activity
uptake of potassium [pubmed|28420751]
K+/H+ symport [pubmed|32005818,28420751]
The protein
Protein family
[SW|amino acid-polyamine-organocation (APC) superfamily] (according to UniProt)
KUP family (single member) [pubmed|32005818]
[SW|amino acid-polyamine-organocation (APC) superfamily] (according to UniProt)
The protein
[SW|Domains]
11 trans-membrane helices at the N-terminus [pubmed|28420751]
C-terminal cytoplasmic domain [pubmed|28420751]
12 trans-membrane helices at the N-terminus [pubmed|32005818]
C-terminal cytoplasmic domain [pubmed|28420751]
The protein
Effectors of protein activity
activity is inhibited upon binding of c-di-AMP [pubmed|31061098]
in the Listeria monocytogenes protein, c-di-AMP binds to the C-terminal cytoplasmatic domain of KimA [pubmed|31506295]
activity is inhibited upon binding of c-di-AMP [pubmed|31061098]
in the Listeria monocytogenes protein, c-di-AMP binds to the C-terminal cytoplasmic domain of KimA [pubmed|31506295]
labs
[SW|Jörg Stülke], Göttingen, Germany
[SW|Jörg Stülke], University of Göttingen, Germany [http://genmibio.uni-goettingen.de Homepage]
[SW|Inga Hänelt], Frankfurt, Germany [https://www.biochem.uni-frankfurt.de/index.php?id=298 Homepage]
References
Reviews
References
Original publications
The protein
Kinetic information
KM: 215 µM [pubmed|32005818]
Vmax 245 nmol min−1 mg−1 [pubmed|32005818]
The protein
Structure
[PDB|6S3K] [pubmed|32005818]