SubtiBank SubtiBank
Version comparison:

Mon Aug 31 2015 13:56:03 GMT+0200 (CEST)2025-05-04 00:48:58

locus

BSU28070

BSU_28070

ec

outlinks

bsu

BSU28070

BSU_28070

syns

[SW|Categories] containing this gene/protein

[SW|genetic competence], [SW|protein secretion], [SW|membrane proteins]

The protein

Catalyzed reaction/ biological activity

processing and translocation of [SW|ComGC], [SW|ComGD], [SW|ComGE] and [SW|ComGG] [Pubmed|9723928]

Typically cleaves a -Gly-|-Phe- bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine (according to Swiss-Prot)

processing and translocation of [[protein|ComGC]], [[protein|ComGD]], [[protein|ComGE]] and [[protein|ComGG]] [Pubmed|9723928]

Typically cleaves a -Gly-|-Phe- bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine (according to UniProt)

The protein

Protein family

peptidase A24 family (according to Swiss-Prot)

peptidase A24 family (single member, according to UniProt)

The protein

[SW|Interactions]

[[protein|ComC]]-[SW|ComGC] [Pubmed|9723928]

[[protein|ComC]]-[SW|ComGD] [Pubmed|9723928]

[[protein|ComC]]-[SW|ComGE] [Pubmed|9723928]

[[protein|ComC]]-[SW|ComGG] [Pubmed|9723928]

Expression and Regulation

Operon

''comC'' [Pubmed|1694528]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigA]] [Pubmed|1694528]

Expression and Regulation

Regulatory mechanism

[[protein|ComK]]: transcription activation [Pubmed|8196543]

proteinLength

248

geneLength

747

Gene

Coordinates

2,864,426 2,865,172

The protein

Paralogous protein(s)

[[this]]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

BKE28070 ([[gene|comC]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE28070 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGACAACACACCTTTAC, downstream forward: _UP4_TGACTGCTGAAAAATTTGAC

BKK28070 ([[gene|comC]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK28070 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGACAACACACCTTTAC, downstream forward: _UP4_TGACTGCTGAAAAATTTGAC