Mon Aug 31 2015 13:56:03 GMT+0200 (CEST)2025-05-04 00:48:58
locus
BSU28070
BSU_28070
ec
outlinks
bsu
BSU28070
BSU_28070
syns
[SW|Categories] containing this gene/protein
[SW|genetic competence], [SW|protein secretion], [SW|membrane proteins]
The protein
Catalyzed reaction/ biological activity
processing and translocation of [SW|ComGC], [SW|ComGD], [SW|ComGE] and [SW|ComGG] [Pubmed|9723928]
Typically cleaves a -Gly-|-Phe- bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine (according to Swiss-Prot)
processing and translocation of [[protein|ComGC]], [[protein|ComGD]], [[protein|ComGE]] and [[protein|ComGG]] [Pubmed|9723928]
Typically cleaves a -Gly-|-Phe- bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine (according to UniProt)
The protein
Protein family
peptidase A24 family (according to Swiss-Prot)
peptidase A24 family (single member, according to UniProt)
The protein
[SW|Interactions]
[[protein|ComC]]-[SW|ComGC] [Pubmed|9723928]
[[protein|ComC]]-[SW|ComGD] [Pubmed|9723928]
[[protein|ComC]]-[SW|ComGE] [Pubmed|9723928]
[[protein|ComC]]-[SW|ComGG] [Pubmed|9723928]
Expression and Regulation
Operon
''comC'' [Pubmed|1694528]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|1694528]
Expression and Regulation
Regulatory mechanism
[[protein|ComK]]: transcription activation [Pubmed|8196543]
proteinLength
248
geneLength
747
Gene
Coordinates
2,864,426 2,865,172
The protein
Paralogous protein(s)
[[this]]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE28070 ([[gene|comC]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE28070 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGACAACACACCTTTAC, downstream forward: _UP4_TGACTGCTGAAAAATTTGAC
BKK28070 ([[gene|comC]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK28070 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGACAACACACCTTTAC, downstream forward: _UP4_TGACTGCTGAAAAATTTGAC