SubtiBank SubtiBank
Version comparison:

2017-8-11 16:0:32025-05-22 18:24:39

description

glycine betaine ABC transporter (binding protein)

glycine betaine and arsenobetaine [SW|ABC transporter] (binding protein)

locus

BSU03000

BSU_03000

geneLength

879

882

product

glycine betaine ABC transporter (binding protein)

glycine betaine and arsenobetaine [SW|ABC transporter] (binding protein)

ec

outlinks

bsu

BSU03000

BSU_03000

Gene

Coordinates

323,119 → 324,000

323,119 324,000

The protein

Catalyzed reaction/ biological activity

binding for subsequent uptake of glycine betaine [Pubmed|24561588]

binding for subsequent uptake of dimethylglycine [Pubmed|24561588]

binding for subsequent uptake of glycine betaine and arsenobetaine [pubmed|29159878,24561588]

binding for subsequent uptake of dimethylglycine [Pubmed|24561588]

The protein

Structure

[PDB|2B4L] (complex with glycine betaine), [PDB|3CHG] (in complex with DMSA)

[PDB|2B4L] (complex with glycine betaine)

[PDB|3CHG] (in complex with DMSA)

[PDB|5NXX] (in complex with arsenobetaine) [pubmed|29159878]

Biological materials

Expression vector

pGP2926 (N-terminal His-tag, purification from ''E. coli'', in [SW|pWH844]), available in [SW|Jörg Stülke]'s lab

Labs working on this gene/protein

[SW|Erhard Bremer], University of Marburg, Germany [http://www.uni-marburg.de/fb17/fachgebiete/mikrobio/molmibi homepage]

References

Original publications

10092453, 9335265, 16645306, 16225868, 16445940, 7622480, 18567662, 21296969, 22383849, 23175650, 23646920, 24561588, 25012968

10092453, 9335265, 16645306, 16225868, 16445940, 7622480, 18567662, 21296969, 22383849, 23175650, 23646920, 24561588, 25012968, 29159878

The protein

Paralogous protein(s)

[[this]]

Biological materials

Mutant

BKE03000 ([[gene|opuAC]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE03000 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GATGCCTATGATTTTTTTAA, downstream forward: _UP4_TAATCAAAAAAGCAGCCTGT

BKK03000 ([[gene|opuAC]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK03000 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GATGCCTATGATTTTTTTAA, downstream forward: _UP4_TAATCAAAAAAGCAGCCTGT

Biological materials

Expression vectors

pGP2926 (N-terminal His-tag, purification from ''E. coli'', in [SW|pWH844]), available in [SW|Jörg Stülke]'s lab

labs

[SW|Erhard Bremer], University of Marburg, Germany [http://www.uni-marburg.de/fb17/fachgebiete/mikrobio/molmibi homepage]