SubtiBank SubtiBank
Version comparison:

2017-8-11 16:0:3Tue Dec 13 2016 11:16:30 GMT+0100 (CET)

proteinLength

478

geneLength

1434

Gene

Coordinates

449,724 → 451,160

The protein

Protein family

[[protein|PtsI]] permease, fructose/ mannitol permease (Fru) family [Pubmed|10627040]

[SW|PTS] permease, fructose/ mannitol permease (Fru) family [Pubmed|10627040]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

MGNA-C018 (mtlA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2016 NBRP B. subtilis, Japan]

aminos

MQQQEQQQGGMKVKVQRFGSYLSGMIMPNIGAFIAWGIITALFIPAGWFPNEQLNTLVSPMITYLLPLLIAYTGGKMIYDHRGGVVGATAAIGVIVGSDIPMFLGAMIMGPLGGYLIKQTDKLFKDKVKQGFEMLINNFTAGIVGAALTILAFYAIGPVVLTLNKLLAAGVEVIVHANLLPVASVFVEPAKVLFLNNAINHGILSPIGIEQASQTGKSILFLVEANPGPGLGILLAYMFFGKGSSKSTAPGAAIIHFFGGIHEIYFPYILMKPALILAAIAGGASGLLTFTIFNAGLVAAASPGSIIALMAMTPRGGYFGVLAGVLVAAAVSFIVSAVILKSSKASEEDLAAATEKMQSMKGKKSQAAAALEAEQAKAEEASELSPESVNKIIFACDAGMGSSAMGASILRNKVKKAELDISVTNTAINNLPSDADIVITHKDLTDRAKAKLPNATHISVDNFLNSPKYDELIEKLKK

[SW|Categories] containing this gene/protein

[SW|phosphotransferase systems], [SW|utilization of specific carbon sources], [SW|transcription factors and their control], [SW|trigger enzyme], [SW|membrane proteins], [SW|phosphoproteins]

Gene

Coordinates on the chromosome (coding sequence)

449,724 -> 451,160

The protein

[SW|Interactions]

[[protein|MtlA]]-[[protein|MtlR]] [Pubmed|20444094] (the non-phosphorylated IIB domain of [[protein|MtlA]] interacts with the two C-terminal EIIB (Gat)-like and EIIA (Mtl)-like domains of [[protein|MtlR]]) [Pubmed|23279188]

Expression and Regulation

Operon

''[[protein|mtlA]]-[[protein|mtlF]]-[[protein|mtlD]]'' [Pubmed|12897001]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigA]] [Pubmed|22014119]

Expression and Regulation

Regulation

induced by mannitol ([[protein|MtlR]]) [Pubmed|20444094]

repressed by glucose ([[protein|MtlR]]) [Pubmed|20444094]

Expression and Regulation

Regulatory mechanism

[[protein|MtlR]]: transcription activation [Pubmed|20444094]