Wed Dec 21 2016 17:14:38 GMT+0100 (CET)2025-05-05 22:52:02
description
similar to molecular chaperone
putative guanidine exporter
locus
BSU13100
BSU_13100
function
unknown
export/ detoxification of guanidine
product
unknown
subunit of guanidine exporter
ec
outlinks
bsu
BSU13100
BSU_13100
[SW|Categories] containing this gene/protein
[SW|chaperones/ protein folding], [SW|membrane proteins]
Gene
Coordinates on the chromosome (coding sequence)
1,376,855 -> 1,377,172
The protein
Protein family
View classification (according to Swiss-Prot)
paired small multidrug resistance protein family ([SW|PSMR family]) [Pubmed|17942072]
[SW|drug/metabolite transporter (DMT) superfamily] (according to UniProt)
[SW|Small multidrug resistance (SMR) (TC 2.A.7.1) family] (according to UniProt)
The protein
[SW|Localization]
cell membrane (according to Swiss-Prot)
cell membrane (according to UniProt)
Expression and Regulation
Operon
''[[protein|ykkC]]-[[protein|ykkD]]'' [Pubmed|10735877]
Expression and Regulation
Regulation
induced in the presence of guanidine ([SW|ykkC riboswitch]) [Pubmed|27989440]
Expression and Regulation
Regulatory mechanism
[SW|ykkC riboswitch]: binding of the lingand guanidine causes transcriptional antitermination [Pubmed|27989440]
term-seq has identified a potential novel regulatory RNA element including an intrinsic transcription terminator upstream of ''ykkC'' [Pubmed|27120414]
Biological materials
Mutant
MGNA-A748 (ykkD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/748 NBRP B. subtilis, Japan]
MGNA-A748 (ykkD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/748 NBRP B. subtilis, Japan]
BKE13100 ([[gene|ykkD]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE13100 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATAAACTGATCCAGTGCA, downstream forward: _UP4_TAAATTGATTTTTATCAAAT
BKK13100 ([[gene|ykkD]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK13100 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATAAACTGATCCAGTGCA, downstream forward: _UP4_TAAATTGATTTTTATCAAAT
References
proteinLength
105
geneLength
318
Gene
Coordinates
1,376,855 1,377,172
The protein
Paralogous protein(s)
[[this]]
The protein
Structure
[PDB|3B5D] (from E. coli, 29% identity) [pubmed|18024586]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
References
Reviews
References
Original publications