BSU15290

BSU_15290

cell-division initiation protein (septum formation)

cell-division initiation protein (septum formation), member of the [SW|divisome]

BSU15290

BSU_15290

[SW|cell division], [SW|essential genes], [SW|membrane proteins]

1,597,832 -> 1,598,980

ftsZ family (according to Swiss-Prot)

FtsZ family (single member, according to UniProt)

[PDB|2VAM]

[PDB|2RHL] (dimer with GDP)

[PDB|4U39] ([[protein|FtsZ]]-[[protein|MciZ]] complex) [Pubmed|25848052]

[PDB|2VAM]

[PDB|2RHL] (dimer with GDP)

[PDB|4U39] ([[protein|FtsZ]]-[[protein|F150B9B75C8352950B9BB71E29CB156B66AA6CDD]] complex) [Pubmed|25848052]

septal at the cell membrane [Pubmed|20566861]

septal localization partially depends on the proton motive force [Pubmed|20566861]

[[protein|Noc]] and the Min system ensure the efficient utilization of the division site at midcell in by ensuring [[FtsZ|Z ring]] placement [Pubmed|22457634]

[[protein|FtsZ]] is anchored to the cell membrane by either [[protein|FtsA]] or [[protein|SepF]] [Pubmed|24218584,16159787]

septal at the cell membrane [Pubmed|20566861]

septal localization partially depends on the proton motive force [Pubmed|20566861]

[[protein|Noc]] and the Min system ensure the efficient utilization of the division site at midcell in by ensuring [[protein|FtsZ|Z ring]]]] placement [Pubmed|22457634]

[[protein|FtsZ]] is anchored to the cell membrane by either [[protein|FtsA]] or [[protein|SepF]] [Pubmed|24218584,16159787]

[[protein|FtsZ]]-[[protein|ZapA]] [Pubmed|19843223]

[[protein|FtsZ]]-[[protein|EzrA]] [Pubmed|25403286,10449747]

[[protein|FtsZ]]-[SW|SpoIIE]

[[protein|FtsZ]]-[[protein|FtsA]] [Pubmed|16159787]

[[protein|FtsZ]]-[[protein|FtsZ]] [Pubmed|17662947]

[[protein|MciZ]]-[[protein|FtsZ]] [Pubmed|18284588], K_D: 150 nM [Pubmed|25848052]

[[protein|FtsZ]] (extreme C terminus of [[protein|FtsZ]])-[[protein|SepF]] [Pubmed|24218584,22912848,16420366]

[[protein|RefZ]]-[[protein|FtsZ]] [Pubmed|22730127]

[[protein|FtsZ]]-[[protein|LytE]] [Pubmed|16950129]

[[protein|UgtP]]-[[protein|FtsZ]], this interaction inhibits [[protein|FtsZ]] filament formation [Pubmed|22931116]

[[protein|FtsZ]] (C-terminal domain)-[[protein|MinC]] [Pubmed|23577149]

[[protein|WalK]]-[[protein|FtsZ]] [Pubmed|18573169]

the novel antibiotic ADEP (acyldepsipeptides) causes [[protein|FtsZ]] degradation via dysregulation [[protein|ClpP]] activity (activity occurs even in the absence of an ATPase subunit ([[protein|ClpC]], [[protein|ClpE]], or [[protein|ClpX]])) [Pubmed|21969594]

the novel antibiotic ADEP (acyldepsipeptides) causes [[protein|FtsZ]] degradation via dysregulation [[protein|ClpP]] activity (activity occurs even in the absence of an ATPase subunit ([[protein|ClpC]], [[protein|ClpE]], or [[protein|ClpX]])) [Pubmed|21969594]

[[protein|FtsZ]] is unfolded for N-terminal degradation by antibiotic-activated [[protein|ClpP]] [pubmed|32605984]

''[[protein|ftsA]]-[[protein|ftsZ]]'' [Pubmed|1569582]

[[protein|SigA]] [Pubmed|1569582], [[protein|SigH]] [Pubmed|1569582]

activated by [[protein|WalR]] [Pubmed|10878122]

half-life of the ''[SW|ftsZ]'' mRNA: 2.2 min [Pubmed|26110430]

GP2009: expression of ''ftsZ''-Strep under control of the ''ftsZ'' promoter (based on [SW|pGP1389]), available in [SW|Jörg Stülke]'s lab

[SW|Imrich Barak], Slovak Academy of Science, Bratislava, Slovakia [http://imb.savba.sk/~barak/ homepage]

[SW|Leendert Hamoen], CBCB, Newcastle University, UK

22047950, 22575476, 21119015, 19680248, 19884039, 17506674, 15037301, 21047262, 21981908, 24550892, 25957405, 26706151, 27620716

22047950, 22575476, 21119015, 19680248, 19884039, 17506674, 15037301, 21047262, 21981908, 24550892, 25957405, 26706151, 27620716, 28254403, 28500523, 28697666, 28975672, 29355854, 30855188

19583568, 20410587, 16174771, 20212044, 20615583, 21276094, 23841620, 23855511, 24079270, 24749867, 25062781, 25972861, 26258635

19583568, 20410587, 16174771, 20212044, 20615583, 21276094, 23841620, 23855511, 24079270, 24749867, 25062781, 25972861, 26258635, 28082038, 28168121, 31249557

24007276, 15288790, 15317782, 12180929, 9364910, 10323866, 19212404, 15942012, 12007411, 16420366, 25176632, 16159787, 10747015, 16950129, 16796675, 10322023, 9495766, 9287012, 1569582, 10878122, 17718511, 11395470, 10449747, 17662947, 12368265, 18284588, 8600030, 18588879, 7592498, 19136590, 19429628, 19141479, 19843223, 16484179, 20199598, 20566861, 20711458, 20807205, 20933427, 15948963, 12700262, 22298780, 22457634, 22730127, 22984350, 23577149, 22931116, 22912848, 21224850, 23692518, 23701187, 23836667, 16159787, 24300445, 24316672, 24825009, 18573169, 25403286, 25358088, 25848052, 26247422, 23098212, 23237472, 26601800, 26360512, 27410746, 27629358, 27752253

24007276, 15288790, 15317782, 12180929, 9364910, 10323866, 19212404, 15942012, 12007411, 16420366, 25176632, 16159787, 10747015, 16950129, 16796675, 10322023, 9495766, 9287012, 1569582, 10878122, 17718511, 11395470, 10449747, 17662947, 12368265, 18284588, 8600030, 18588879, 7592498, 19136590, 19429628, 19141479, 19843223, 16484179, 20199598, 20566861, 20711458, 20807205, 20933427, 15948963, 12700262, 22298780, 22457634, 22730127, 22984350, 23577149, 22931116, 22912848, 21224850, 23692518, 23701187, 23836667, 16159787, 24300445, 24316672, 24825009, 18573169, 25403286, 25358088, 25848052, 26247422, 23098212, 23237472, 26601800, 26360512, 27410746, 27629358, 27752253, 28465423, 28616148, 30636070, 32184253, 32198113, 32605984, 33077634

382

1149

1,597,832 1,598,980

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GP2009: expression of ''ftsZ''-Strep under control of the ''ftsZ'' promoter (based on [SW|pGP1389]), available in [SW|Jörg Stülke]'s lab

[SW|Imrich Barak], Slovak Academy of Science, Bratislava, Slovakia [http://imb.savba.sk/~barak/ homepage]

[SW|Leendert Hamoen], CBCB, Newcastle University, UK