Tue Dec 13 2016 11:16:35 GMT+0100 (CET)2025-07-27 02:20:23
description
transcriptional repressor of the fatR-yrhJ operon
transcriptional repressor of the [[gene|fatR]]-[[gene|yrhJ]] operon
locus
BSU27170
BSU_27170
product
transcriptional repressor
of the fatR-yrhJ operon (TetR family)
transcriptional repressor of the [[gene|fatR]]-[[gene|yrhJ]] operon ([SW|TetR family])
ec
outlinks
bsu
BSU27170
BSU_27170
aminos
MISASSSKYDMIMKASVSLFTERGFDATTIPMIAERAHVGTGTIYRYFDSKETLVNVLFQESIQRFTEKLKQDVSELPVREGFHHVFCCLVQFTKESDYALFFLETKKDAHYLNHTSKKMIENLTQMLDDYFNKGKAEGVIRSLPSNVLIAIVLGAFLKIYQLVQTGDIEMDTDLITELEQCCWDAIKLHSSQK
[SW|Categories] containing this gene/protein
[SW|electron transport/ other], [SW|lipid metabolism/ other], [SW|transcription factors and their control], [SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)], [SW|phosphoproteins]
Gene
Coordinates on the chromosome (coding sequence)
2,777,070 -> 2,777,654
The protein
[SW|Interactions]
[[protein|FatR]]-[[protein|TkmA]] [Pubmed|23939619]
[[protein|FatR]]-[[protein|PtkA]] [Pubmed|23939619]
Expression and Regulation
Operon
''[[protein|fatR]]-[[protein|yrhJ]]'' [Pubmed|10917605]
''[[protein|yrhH]]-[[protein|fatR]]-[[protein|yrhJ]]'' [Pubmed|18179421]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigM]] [Pubmed|18179421], [[protein|SigW]] [Pubmed|12207695], [[protein|SigX]] [Pubmed|9636707]
Expression and Regulation
Regulation
induced by unsaturated fatty acids ([[protein|FatR]]) [Pubmed|11734890]
expression is reduced in a [[protein|SigV]] mutant [Pubmed|21926231]
Expression and Regulation
Regulatory mechanism
[[protein|FatR]]: transcription repression [Pubmed|11734890]
proteinLength
194
geneLength
585
Gene
Coordinates
2,777,070 2,777,654
The protein
Protein family
[SW|TetR family]
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Domains]
[SW|HTH tetR-type domain] (aa 6-66) (according to UniProt)
The protein
Structure
[PDB|4ME9] (from B. cereus, 38% identity)
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
MGNA-A177 (yrhI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/177 NBRP B. subtilis, Japan]
BKE27170 ([[gene|fatR]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE27170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTAATCTGACAACCTCC, downstream forward: _UP4_CAAAAATAGGAAAGGGAGAT
BKK27170 ([[gene|fatR]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK27170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTAATCTGACAACCTCC, downstream forward: _UP4_CAAAAATAGGAAAGGGAGAT