Mon Aug 31 2015 13:55:18 GMT+0200 (CEST)2025-05-23 19:46:48
locus
BSU22740
BSU_22740
product
heptaprenyl diphosphate synthase component II (together with HepS)
heptaprenyl diphosphate synthase component II (together with [[protein|HepS]])
essential
yes
no
outlinks
bsu
BSU22740
BSU_22740
[SW|Categories] containing this gene/protein
[SW|biosynthesis of cofactors], [SW|essential genes]
Gene
Coordinates on the chromosome (coding sequence)
2,381,919 -> 2,382,965
Gene
Phenotypes of a mutant
essential [Pubmed|12682299]
essential [Pubmed|12682299], non-essential according to [Pubmed|28189581]
The protein
Catalyzed reaction/ biological activity
All-trans-hexaprenyl diphosphate
(2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate --> all-trans-heptaprenyl diphosphate + 4 diphosphate (according to UniProt)
The protein
Paralogous protein(s)
[[protein|YqiD]]
[[this]]
References
proteinLength
348
geneLength
1047
Gene
Coordinates
2,381,919 2,382,965
The protein
Protein family
FPP/GGPP synthase family (with [[protein|YqiD]], according to UniProt)
The protein
Structure
[PDB|5H9D] (from Staphylococcus aureus, 47% identity) [pubmed|27457559]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE22740 ([[gene|hepT]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE22740 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATCATTCACCCAAACATCTG, downstream forward: _UP4_TAATTTTTGTAGATATTAAG
BKK22740 ([[gene|hepT]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK22740 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATCATTCACCCAAACATCTG, downstream forward: _UP4_TAATTTTTGTAGATATTAAG