Tue Dec 13 2016 11:16:30 GMT+0100 (CET)2025-05-22 13:12:31
locus
BSU02490
BSU_02490
outlinks
bsu
BSU02490
BSU_02490
aminos
MSSPIQEQVQKEKRSNIPSISEMKVIPVAGHDSMLLNLSGAHSPFFTRNIVILTDSSGNQGVGEVPGGEHIRRTLELSEPLVVGKSIGAYQAILQTVRKQFGDQDRGGRGNQTFDLRTTVHAVTALEAALLDLLGKFLQEPVAALLGEGKQRDEVKMLGYLFYIGDRNRTTLPYQSDEQSDCAWFRLRHEEALTPEAIVRLAESAQERYGFQDFKLKGGVLRGEEEIEAVTALSKRFPEARITLDPNGAWSLEEAIALCKGKQDVLAYAEDPCGDENGYSAREVMAEFRRATGLPTATNMIATDWREMGHAIQLHAVDIPLADPHFWTMQGSVRVAQMCHDWGLTWGSHSNNHFDISLAMFTHVAAAAPGRITAIDTHWIWQDGQRLTKQPFEISSGCVKVPDKPGLGVDIDMEQVEKAHEIYRKMNLGARNDAIPMQFLISNWEFDRKRPCLVR
[SW|Categories] containing this gene/protein
[SW|utilization of specific carbon sources]
Gene
Coordinates on the chromosome (coding sequence)
271,800 -> 273,167
The protein
Catalyzed reaction/ biological activity
d-glucarate = 5-dehydro-4-deoxy-D-glucarate + H2O (according to Swiss-Prot)
D-glucarate --> 5-dehydro-4-deoxy-D-glucarate + H2O (according to UniProt)
The protein
Protein family
GlucD subfamily (according to Swiss-Prot)
[SW|mandelate racemase/muconate lactonizing enzyme family] (according to UniProt)
Expression and Regulation
Operon
''[[protein|ycbC]]-[[protein|ycbD]]-[[protein|ycbE]]-[[protein|ycbF]]-[[protein|ycbG]]-[[protein|ycbH]]-[[protein|ycbJ]]'' [Pubmed|12044674]
Expression and Regulation
Regulation
induced by D-glucarate/galactarate ([[protein|YcbG]]) [Pubmed|12044674]
Expression and Regulation
Regulatory mechanism
[[protein|YcbG]]: transcription repression [Pubmed|12044674]
References
proteinLength
455
geneLength
1368
Gene
Coordinates
271,800 273,167
The protein
Paralogous protein(s)
[[this]]
The protein
Structure
[PDB|1EC7] (from E. coli, 73% identity) [pubmed|10769114]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
MGNA-C029 (ycbF::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2027 NBRP B. subtilis, Japan]
BKE02490 ([[gene|ycbF]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE02490 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCATTTTCCTCCCTTTA, downstream forward: _UP4_TAAGTTTGATTGTAAATATT
BKK02490 ([[gene|ycbF]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK02490 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCATTTTCCTCCCTTTA, downstream forward: _UP4_TAAGTTTGATTGTAAATATT