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Tue Dec 13 2016 11:16:31 GMT+0100 (CET)2025-05-15 10:34:14

description

ABC transporter for the siderophore schizokinen and arthrobactin (permease), works with ATPase YusV

[SW|ABC transporter] for the siderophore schizokinen and arthrobactin (permease), works with ATPase [[protein|YusV]]

locus

BSU08460

BSU_08460

function

acquisition of iron

[SW|acquisition of iron]

product

ABC transporter for the siderophore
schizokinen and arthrobactin (permease)

[SW|ABC transporter] for the siderophore schizokinen and arthrobactin (permease)

ec

outlinks

bsu

BSU08460

BSU_08460

aminos

MKLRFGVTAAEKKAWIVFLVLLGLTAAVLIISAGLGQRFIPPWDVAKTFFGAGSKLDELMIMSFRMPRILTALCAGVCLAAAGAILQGLVRNPLASPDIIGITGGAAVAVVLLMMFFSDRSSSLTISLSWLPAAAFIGASAVGLIVYLLAYKNGASTFRLVLIGIGFSMSAQAMTTLLMIKGPIYRASQANVYITGSVYGSNWQHVKIAIILSVILLFICFVALKNMNIQVLGEDIAAGAGSAVQRNRFFLLLLSTALTGCAVSVAGTIGFVGLMAPHIARRLVGSSYGALLPASALIGALLVLTADIVGRTLFAPVEVPAGVFTAAIGAPYFIYLLYKTRNS

[SW|Categories] containing this gene/protein

[SW|ABC transporters], [SW|acquisition of iron], [SW|iron metabolism], [SW|membrane proteins]

Gene

Coordinates on the chromosome (coding sequence)

921,472 -> 922,503

The protein

Protein family

FecCD subfamily (according to Swiss-Prot)

[SW|Binding-protein-dependent transport system permease family] (according to UniProt)

[SW|FecCD subfamily] (according to UniProt)

The protein

[SW|Interactions]

[[protein|YusV]]-([[protein|YfhA]]-[[protein|YfiZ]])-[[protein|YfiY]] [Pubmed|10092453]

Expression and Regulation

Regulation

induced upon iron starvation ([[protein|Fur]]) [Pubmed|12354229]

Expression and Regulation

Regulatory mechanism

[[protein|Fur]]: transcription repression [Pubmed|12354229]

References

10092453, 16672620, 12354229

10092453, 16672620, 12354229, 17158291

proteinLength

343

geneLength

1032

Gene

Coordinates

921,472 922,503

The protein

Paralogous protein(s)

[[this]]

The protein

Structure

[PDB|2NQ2] (complex with [[protein|YusV]]-like protein, from Haemophilus influenzae, 33% identity) [pubmed|17158291]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

MGNA-C313 (yfhA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2311 NBRP B. subtilis, Japan]

BKE08460 ([[gene|yfhA]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE08460 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTTCATAGCTTCGCCCCCCT, downstream forward: _UP4_TAATCGTTACACCCATTTTC

BKK08460 ([[gene|yfhA]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK08460 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTTCATAGCTTCGCCCCCCT, downstream forward: _UP4_TAATCGTTACACCCATTTTC