SubtiBank SubtiBank
Version comparison:

Mon Aug 31 2015 13:56:04 GMT+0200 (CEST)2025-05-11 09:27:28

locus

BSU28140

BSU_28140

outlinks

bsu

BSU28140

BSU_28140

syns

[SW|Categories] containing this gene/protein

[SW|biosynthesis of cofactors]

The protein

Catalyzed reaction/ biological activity

Hydroxymethylbilane = uroporphyrinogen III + H2O (according to Swiss-Prot)

hydroxymethylbilane --> H2O + uroporphyrinogen III (according to UniProt)

Expression and Regulation

Operon

''[[protein|hemA]]-[[protein|hemX]]-[[protein|hemC]]-[[protein|hemD]]-[[protein|hemB]]-[[protein|hemL]]'' [Pubmed|1672867]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigA]] [Pubmed|1672867]

Expression and Regulation

Regulation

induced by hydrogen peroxide ([[protein|PerR]]) [Pubmed|11532148]

Expression and Regulation

Regulatory mechanism

[[protein|PerR]]: transcription repression [Pubmed|11532148]

References

10217486, 1672867, 7628476, 11532148, 22960854

proteinLength

262

geneLength

789

Gene

Coordinates

2,875,173 2,875,961

The protein

Protein family

uroporphyrinogen-III synthase family (single member, according to UniProt)

The protein

Paralogous protein(s)

[[this]]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

BKE28140 ([[gene|hemD]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE28140 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTGTTTTTCCTTTCAACG, downstream forward: _UP4_ATGTCAAGAGAGGAAGAGAG

BKK28140 ([[gene|hemD]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK28140 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTGTTTTTCCTTTCAACG, downstream forward: _UP4_ATGTCAAGAGAGGAAGAGAG

References

Reviews

28123057

References

Original Publications

10217486, 1672867, 7628476, 11532148, 22960854