Mon Aug 31 2015 13:56:04 GMT+0200 (CEST)2025-05-11 09:27:28
locus
BSU28140
BSU_28140
outlinks
bsu
BSU28140
BSU_28140
syns
[SW|Categories] containing this gene/protein
[SW|biosynthesis of cofactors]
The protein
Catalyzed reaction/ biological activity
Hydroxymethylbilane = uroporphyrinogen III + H2O (according to Swiss-Prot)
hydroxymethylbilane --> H2O + uroporphyrinogen III (according to UniProt)
Expression and Regulation
Operon
''[[protein|hemA]]-[[protein|hemX]]-[[protein|hemC]]-[[protein|hemD]]-[[protein|hemB]]-[[protein|hemL]]'' [Pubmed|1672867]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|1672867]
Expression and Regulation
Regulation
induced by hydrogen peroxide ([[protein|PerR]]) [Pubmed|11532148]
Expression and Regulation
Regulatory mechanism
[[protein|PerR]]: transcription repression [Pubmed|11532148]
References
proteinLength
262
geneLength
789
Gene
Coordinates
2,875,173 2,875,961
The protein
Protein family
uroporphyrinogen-III synthase family (single member, according to UniProt)
The protein
Paralogous protein(s)
[[this]]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE28140 ([[gene|hemD]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE28140 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTGTTTTTCCTTTCAACG, downstream forward: _UP4_ATGTCAAGAGAGGAAGAGAG
BKK28140 ([[gene|hemD]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK28140 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTGTTTTTCCTTTCAACG, downstream forward: _UP4_ATGTCAAGAGAGGAAGAGAG
References
Reviews
References
Original Publications