SubtiBank SubtiBank
Version comparison:

2017-8-11 16:0:3Tue Dec 13 2016 11:16:31 GMT+0100 (CET)

proteinLength

458

geneLength

1374

Gene

Coordinates

882,266 → 883,642

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

MGNA-C351 (acoL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2349 NBRP B. subtilis, Japan]

aminos

MTLAIIGGGPAGYAAAVSAAQQGRNVLLIDKGKLGGTCLNEGCIPTKSLLESANVLDKIKHADSFGIELPAGAISVDWSKMQSRKQQVVSQLVQGVQYLMKKNQIQVVKGTASFLSERKLLIEGENGKEIREADQVLIASGSEPIELPFAPFDGEWILDSKDALSLSEIPSSLVIVGGGVIGCEYAGLFARLGSQVTIIETADRLIPAEDEDIARLFQEKLEEDGVEVHTSSRLGRVDQTAKTAIWKSGQREFKTKADYVLVAIGRKPRLDGLQLEQAGVDFSPKGIPVNGHMQTNVPHIYACGDAIGGIQLAHAAFHEGIIAASHASGRDVKINEKHVPRCIYTSPEIACIGMTERQARSIYGDVKIGEFSFSANGKALIKQQAEGKVKIMAEPEFGEIVGVSMIGPDVTELIGQAAAIMNGEMTADMAEHFIAAHPTLSETLHEALLSTIGLAVHA

[SW|Categories] containing this gene/protein

[SW|utilization of specific carbon sources], [SW|sporulation proteins]

Gene

Coordinates on the chromosome (coding sequence)

882,266 -> 883,642

The protein

[SW|Interactions]

([[protein|AcoA]]-[[protein|AcoB]])-[[protein|AcoC]]-[[protein|AcoL]]

Expression and Regulation

Operon

''[[protein|acoA]]-[[protein|acoB]]-[[protein|acoC]]-[[protein|acoL]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/11274109 PubMed]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigL]] [http://www.ncbi.nlm.nih.gov/sites/entrez/11274109 PubMed]

Expression and Regulation

Regulation

repressed by glucose ([[protein|CcpA]]) [Pubmed|10666464]

induced by acetoin ([[protein|AcoR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/11274109 PubMed]

induced under anaerobic conditions ([[protein|Fnr]]) [Pubmed|16428414]

Expression and Regulation

Regulatory mechanism

[[protein|CcpA]]: transcription repression [Pubmed|10666464]

[[protein|AcoR]]: transcription activation (interaction with [[protein|SigL]]-containing [SW|RNA polymerase]) [http://www.ncbi.nlm.nih.gov/sites/entrez/11274109 PubMed]

[[protein|Fnr]]: indirect positive regulation via [[protein|NarG]]-[[protein|NarH]]-[[protein|NarJ]]-[[protein|NarI]] [Pubmed|16428414]

Expression and Regulation

Additional information

the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]

the mRNA is substantially stabilized upon depletion of [[Rny|RNase Y]] [PubMed|21815947]