SubtiBank SubtiBank
Version comparison:

Mon Aug 31 2015 13:52:51 GMT+0200 (CEST)2025-05-27 16:27:23

locus

BSU06150

BSU_06150

outlinks

bsu

BSU06150

BSU_06150

syns

[SW|Categories] containing this gene/protein

[SW|utilization of specific carbon sources]

The protein

Catalyzed reaction/ biological activity

L-iditol + NAD+ = L-sorbose + NADH (according to Swiss-Prot)

D-fructose + H+ + NADH --> D-sorbitol + NAD+ (according to UniProt)

NAD+ + xylitol --> D-xylulose + H+ + NADH (according to UniProt)

L-iditol + NAD+ --> H+ + L-sorbose + NADH (according to UniProt)

The protein

Protein family

zinc-containing alcohol dehydrogenase family (according to Swiss-Prot)

[SW|zinc-containing alcohol dehydrogenase family] (according to UniProt)

Expression and Regulation

Operon

''[[protein|gutB]]-[[protein|gutP]]'' [Pubmed|12897001]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigA]] [Pubmed|8195086]

Expression and Regulation

Regulation

induced by glucitol ([[protein|GutR]]) [Pubmed|8195086]

Expression and Regulation

Regulatory mechanism

[[protein|GutR]]: transcriptional activation [Pubmed|8195086]

References

1460002, 12897001, 8195086

1460002, 12897001, 8195086, 12962626

proteinLength

353

geneLength

1062

Gene

Coordinates

667,466 668,527

The protein

Paralogous protein(s)

[[this]]

The protein

[SW|Cofactors]

NAD+ (according to UniProt)

The protein

Structure

[PDB|1PL7] (the human enzyme, 42% identity) [pubmed|12962626]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

BKE06150 ([[gene|gutB]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE06150 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGGCAAGTTCCTTTCT, downstream forward: _UP4_TGAGTGAACAGGGAGGATCT

BKK06150 ([[gene|gutB]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK06150 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGGCAAGTTCCTTTCT, downstream forward: _UP4_TGAGTGAACAGGGAGGATCT