Tue Dec 13 2016 11:16:37 GMT+0100 (CET)2025-05-12 21:17:24
locus
BSU37710
BSU_37710
outlinks
bsu
BSU37710
BSU_37710
aminos
MERKTVLVIADLGGCPPHMFYKSAAEKYNLVSFIPRPFAITASHAALIEKYSVAVIKDKDYFKSLADFEHPDSIYWAHEDHNKPEEEVVEQIVKVAEMFGADAITTNNELFIAPMAKACERLGLRGAGVQAAENARDKNKMRDAFNKAGVKSIKNKRVTTLEDFRAALEEIGTPLILKPTYLASSIGVTLITDTETAEDEFNRVNDYLKSINVPKAVTFEAPFIAEEFLQGEYGDWYQTEGYSDYISIEGIMADGEYFPIAIHDKTPQIGFTETSHITPSILDEEAKKKIVEAAKKANEGLGLQNCATHTEIKLMKNREPGLIESAARFAGWNMIPNIKKVFGLDMAQLLLDVLCFGKDADLPDGLLDQEPYYVADCHLYPQHFKQNGQIPETAEDLVIEAIDIPDGLLKGDTEIVSFSAAAPGTSVDLTLFEAFNSIAAFELKGSNSQDVAESIRQIQQHAKLTAKYVLPV
[SW|Categories] containing this gene/protein
[SW|miscellaneous metabolic pathways], [SW|biosynthesis of antibacterial compounds]
Gene
Coordinates on the chromosome (coding sequence)
3,870,668 -> 3,872,086
The protein
Catalyzed reaction/ biological activity
ligation of anticapsin to L-Ala to form bacilysin, ultimate step in bacilysin biosynthesis [Pubmed|23317005]
ligation of anticapsin to L-Ala to form bacilysin, ultimate step in bacilysin biosynthesis [Pubmed|23317005]
ATP + L-alanine + L-anticapsin --> ADP + bacilysin + H+ + phosphate (according to UniProt)
Expression and Regulation
Operon
''[[protein|bacA]]-[[protein|bacB]]-[[protein|bacC]]-[[protein|bacD]]-[[protein|bacE]]-[[protein|bacF]]'' [Pubmed|12372825]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|19801406]
Expression and Regulation
Regulatory mechanism
[[protein|CodY]]: transcription repression [Pubmed|12372825,21709425]
[[protein|AbrB]]: transcription repression [Pubmed|12697329,21709425]
[[protein|ScoC]]: transcription repression [Pubmed|19801406]
proteinLength
472
geneLength
1419
Gene
Coordinates
3,870,668 3,872,086
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Domains]
[SW|ATP-grasp doamin] (aa 142-355) (according to UniProt)
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
MGNA-B241 (ywfE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1240 NBRP B. subtilis, Japan]
BKE37710 ([[gene|bacD]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE37710 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CTCCATATGTAAAACACTCC, downstream forward: _UP4_ACGGCAAAGTATGTGCTGCC
BKK37710 ([[gene|bacD]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK37710 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CTCCATATGTAAAACACTCC, downstream forward: _UP4_ACGGCAAAGTATGTGCTGCC