SubtiBank SubtiBank
Version comparison:

2019-03-25 12:33:062025-03-30 13:53:57

locus

BSU00880

BSU_00880

outlinks

bsu

BSU00880

BSU_00880

The protein

Catalyzed reaction/ biological activity

synthesis of c-di-AMP from two molecules of ATP [Pubmed|23192352,21566650]

synthesis of c-di-AMP from two molecules of ATP [Pubmed|23192352,21566650]

binds [[protein|RecA]] to inhibit its activity [pubmed|30916351]

2 ATP --> c-di-AMP + 2 diphosphate (according to UniProt)

The protein

Protein family

disA family (according to Swiss-Prot)

DisA family (single member, according to UniProt)

The protein

[SW|Domains]

contains a [SW|DAC domain] for the synthesis of c-di-AMP [Pubmed|18439896]

contains a [SW|DAC domain] for the synthesis of c-di-AMP [Pubmed|18439896]

[SW|DAC domain] (aa 11-149) (according to UniProt)

The protein

[SW|Localization]

see a [http://download.cell.com/mmcs/journals/0092-8674/PIIS0092867406005034.mmc12.avi video] showing the movement of DisA in the cell (in real time) [Pubmed|16713562]

forms discrete globular foci in germinating spres that colocalize with the nucleoid [Pubmed|24244006]

see a [http://download.cell.com/mmcs/journals/0092-8674/PIIS0092867406005034.mmc12.avi video] showing the movement of DisA in the cell (in real time) [Pubmed|16713562]

forms discrete globular foci in germinating spres that colocalize with the nucleoid [Pubmed|24244006]

forms rapidly moving focus that pauses at [[protein|RecA]]-mediated recombination intermediates upon induction of DNA damage during spore development [pubmed|30916351]

References

Reviews

22933559, 18714086, 25869574, 23812326, 30224435

22933559, 18714086, 25869574, 23812326, 30224435, 32472931, 32603625

References

Original publications

24244006, 8793870, 9987115, 16713562, 23760274, 11544224, 17434969, 18439896, 16713555, 12493822, 21566650, 23192352, 23608499, 25616256, 26014055, 27150552, 28420751, 28511132, 28961460, 29536659, 29588402

24244006, 8793870, 9987115, 16713562, 23760274, 11544224, 17434969, 18439896, 16713555, 12493822, 21566650, 23192352, 23608499, 25616256, 26014055, 27150552, 28420751, 28511132, 28961460, 29536659, 29588402, 30877841, 30916351