2019-03-25 12:33:062025-03-30 13:53:57
locus
BSU00880
BSU_00880
outlinks
bsu
BSU00880
BSU_00880
The protein
Catalyzed reaction/ biological activity
synthesis of c-di-AMP from two molecules of ATP [Pubmed|23192352,21566650]
synthesis of c-di-AMP from two molecules of ATP [Pubmed|23192352,21566650]
binds [[protein|RecA]] to inhibit its activity [pubmed|30916351]
2 ATP --> c-di-AMP + 2 diphosphate (according to UniProt)
The protein
Protein family
disA family (according to Swiss-Prot)
DisA family (single member, according to UniProt)
The protein
[SW|Domains]
contains a [SW|DAC domain] for the synthesis of c-di-AMP [Pubmed|18439896]
contains a [SW|DAC domain] for the synthesis of c-di-AMP [Pubmed|18439896]
[SW|DAC domain] (aa 11-149) (according to UniProt)
The protein
[SW|Localization]
see a [http://download.cell.com/mmcs/journals/0092-8674/PIIS0092867406005034.mmc12.avi video] showing the movement of DisA in the cell (in real time) [Pubmed|16713562]
forms discrete globular foci in germinating spres that colocalize with the nucleoid [Pubmed|24244006]
see a [http://download.cell.com/mmcs/journals/0092-8674/PIIS0092867406005034.mmc12.avi video] showing the movement of DisA in the cell (in real time) [Pubmed|16713562]
forms discrete globular foci in germinating spres that colocalize with the nucleoid [Pubmed|24244006]
forms rapidly moving focus that pauses at [[protein|RecA]]-mediated recombination intermediates upon induction of DNA damage during spore development [pubmed|30916351]
References
Reviews
References
Original publications