Mon Aug 31 2015 13:56:51 GMT+0200 (CEST)2025-05-31 19:48:18
description
transcriptional repressor (ArsR family) of the sdpR-sdpI operon
transcriptional repressor ([SW|ArsR family]) of the [[gene|sdpR]]-[[gene|sdpI ]]operon
locus
BSU33790
BSU_33790
function
regulation of protection against SdpC
regulation of protection against [[protein|SdpC]]
product
transcriptional regulator (ArsR family)
transcriptional regulator ([SW|ArsR family])
ec
outlinks
bsu
BSU33790
BSU_33790
syns
yvbA
[SW|Categories] containing this gene/protein
[SW|transcription factors and their control], [SW|toxins, antitoxins and immunity against toxins]
The protein
Effectors of protein activity
[[protein|SdpI]] binds and sequesters [[protein|SdpR]] if extracellular [[protein|SdpC]] is present, this results in induction of the ''[[protein|sdpR]]-[[protein|sdpI]]'' operon [Pubmed|16469701]
[[protein|SdpI]] binds and sequesters [[protein|SdpR]] if extracellular [[protein|SdpC]] is present, this results in induction of the ''[[gene|sdpR]]-[[gene|sdpI]]'' operon [Pubmed|16469701]
The protein
[SW|Interactions]
[[protein|SdpI]]-[[protein|SdpR]] [Pubmed|16469701]
Expression and Regulation
Operon
''[[protein|sdpR]]-[[protein|sdpI]]'' [Pubmed|12817086]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|16469701]
Expression and Regulation
Regulation
repressed during logrithmic growth ([[protein|AbrB]]) [Pubmed|16469701]
induced by extracellular [[protein|SdpC]] ([[protein|SdpR]]) [Pubmed|16469701]
Expression and Regulation
Regulatory mechanism
[[protein|AbrB]]: transcription repression [Pubmed|16469701]
[[protein|SdpR]]: transcription repression [Pubmed|16469701]
proteinLength
90
geneLength
273
Gene
Coordinates
3,467,054 3,467,326
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Domains]
[SW|HTH arsR-type domain] (aa 1-87) (according to UniProt)
The protein
Structure
[PDB|2CWE] (from Pyrococcus horikoshii, 34% identity)
The protein
additional information
information on binding sites can be found in the [http://www.prodoric2.de/detail.php?acc=MX000211 PRODORIC2 database]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE33790 ([[gene|sdpR]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE33790 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGCGTTTTCTCCTTTAC, downstream forward: _UP4_TTATGAAGAAAAATATAATT
BKK33790 ([[gene|sdpR]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK33790 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGCGTTTTCTCCTTTAC, downstream forward: _UP4_TTATGAAGAAAAATATAATT