Tue Dec 13 2016 11:16:37 GMT+0100 (CET)2025-05-07 18:29:11
locus
BSU38730
BSU_38730
ec
outlinks
bsu
BSU38730
BSU_38730
aminos
MKKEEWILPYIKQNARLFVLVIFLGAVTIFSAAFLMFTSGFLISKAATRPENILLIYVPIVAVRTFGIARSVSRYVERLVGHHIILKIVSDMRVRLYNMLEPGALMLRSRFRTGDMLGILSEDIEHLQDAFLKTIFPAISALLLYAVSVIALGFFSWPFAILLALYLFVLVVLFPVVSLLVTRAKNAKLKSGRNVLYSRLTDAVMGVSDWMFSGRRHAFIDAYEKEERDWFELERKKQRFTRWRDFAAQCLVAGLILLMLFWTAGQQADGELAKTMIAAFVLVVFPLTEAFLPLSDALGEVPGYQDSIRRMNNVAPQPEASQTESGDQILDLQDVTLAFRDVTFSYDNSSQVLHNFSFTLRQGEKMALLGRSGSGKSTSLALIEGALKPDSGSVTLNGVETALLKDQIADAVAVLNQKPHLFDTSILNNIRLGNGEASDEDVRRAAKQVKLHDYIESLPDGYHTSVQETGIRFSGGERQRIALARILLQDTPIIILDEPTVGLDPITERELMETVFEVLKGKTILWITHHLAGVEAADKIVFLENGKTEMEGTHEELLAANERYRRLYHLDVPVK
[SW|Categories] containing this gene/protein
[SW|ABC transporters], [SW|respiration], [SW|membrane proteins]
Gene
Coordinates on the chromosome (coding sequence)
3,973,364 -> 3,975,091
The protein
[SW|Domains]
has both a membrane-spanning and an ATP-binding domain [Pubmed|10092453]
has both a membrane-spanning and an ATP-binding domain [Pubmed|10092453]
[SW|ABC transmembrane type-1 domain] (aa 18-303) (according to UniProt)
[SW|ABC transporter domain] (aa 337-570) (according to UniProt)
The protein
[SW|Interactions]
[[protein|CydD]]-[[protein|CydC]] [Pubmed|10092453]
Expression and Regulation
Operon
''[[protein|cydA]]-[[protein|cydB]]-[[protein|cydC]]-[[protein|cydD]]'' [Pubmed|16207915]
''cydD'' [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=+16497325 PubMed]
Expression and Regulation
[SW|Sigma factor]
''[[protein|cydA]]'':
''[[protein|cydD]]'': [[protein|SigF]] [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=+16497325 PubMed]
Expression and Regulation
Regulation
repressed by glucose ([[protein|CcpA]])
induced under anaerobic conditions ([[protein|Rex]]) [Pubmed|16207915]
expressed under anaerobic conditions ([[protein|ResD]]) [Pubmed|17322317]
Expression and Regulation
Regulatory mechanism
[[protein|CcpA]]: transcription repression
[[protein|Rex]]: transcription repression [Pubmed|15231791]
[[protein|ResD]]: transcription activation [Pubmed|17322317]
References
proteinLength
575
geneLength
1728
Gene
Coordinates
3,973,364 3,975,091
The protein
Protein family
[SW|ABC transporter superfamily] (according to UniProt)
The protein
Paralogous protein(s)
[[this]]
The protein
Structure
[PDB|2HYD] (from Staphylococcus aureus, 28% identity) [pubmed|16943773]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
MGNA-B748 (cydD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1747 NBRP B. subtilis, Japan]
BKE38730 ([[gene|cydD]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE38730 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CGGCAAAATCCATTCTTCTT, downstream forward: _UP4_TAAAAGACAGCCCTAAAAGG
BKK38730 ([[gene|cydD]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK38730 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CGGCAAAATCCATTCTTCTT, downstream forward: _UP4_TAAAAGACAGCCCTAAAAGG