Tue Dec 13 2016 11:16:33 GMT+0100 (CET)2025-05-30 04:41:03
locus
BSU18210
BSU_18210
outlinks
bsu
BSU18210
BSU_18210
aminos
MLMDYEKERTERAERIRKGGAEKYHQSNREKGKLFVRERLSLLFDDDIELEDAFFAECMSDGLPADGVVTAIGKIGGQTVCVMANDSTVKAGSWGAKTVEKIIRIQEIAEKLNCPLIYLVDSAGARITDQINVFPGRRGAGRIFYNQVKLSGRIPQICLLFGPSAAGGAYIPAFCDIVVMVDGNASMYLGSPRMAEMVIGEKVSLEEMGGARMHCSISGCGDILAETEEEAIQLVRAYLSYFPANFQEKAPIHEKRPPKHFETPLADVIPQNQNAPFDMHELIERVIDEDSFFEIKALFAPELLTGLARIHGQPVGIVANQPKVKGGVLFHDSADKAAKFITLCDAFHIPLLFLADIPGFMIGTKVEQAGIIRHGAKMISAMSEATVPKLSVIVRKAYGAGLYAMAGPAFEPDCCLALPTAQIAVMGPEAAVNAVYAKKIAELPEEERAAFISSKREEYKEDINIYRLASEMIIDAVIPANSLRDELAKRLKAYMTKEMTFTNRKHPVYPV
[SW|Categories] containing this gene/protein
[SW|utilization of amino acids], [SW|sporulation proteins]
Gene
Coordinates on the chromosome (coding sequence)
1,949,682 -> 1,951,217
The protein
Catalyzed reaction/ biological activity
3-methylbut-2-enoyl-CoA + Biotin-CO2 ---> 3-methyl-glutaconyl-CoA + biotin [Pubmed|19935659]
3-methylbut-2-enoyl-CoA + Biotin-CO2 -- 3-methyl-glutaconyl-CoA + biotin [Pubmed|19935659]
The protein
Paralogous protein(s)
[[protein|YqjD]]
[[this]]
The protein
[SW|Interactions]
[[protein|YngH]]-[[protein|YngE]] [Pubmed|19935659]
Expression and Regulation
Operon
''[[protein|yngJ]]-[[protein|yngI]]-[[protein|yngH]]-[SW|yngHB]-[[protein|yngG]]-[[protein|yngF]]-[[protein|yngE]]'' [Pubmed|12662922]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigE]] [Pubmed|15699190,12662922]
Expression and Regulation
Regulation
expressed during sporulation in the mother cell ([[protein|SigE]]) [Pubmed|15699190,12662922]
proteinLength
511
geneLength
1536
Gene
Coordinates
1,949,682 1,951,217
The protein
Protein family
AccD/PCCB family (with [[protein|AccD]] and [[protein|YqjD]], according to UniProt)
The protein
[SW|Domains]
CoA carboxyltransferase N-terminal domain (aa 2-254) (according to UniProt)
CoA carboxyltransferase C-terminal domain (aa 260-506) (according to UniProt)
The protein
Structure
[PDB|1VRG] (from Thermotoga maritima, 40% identity)
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
MGNA-B081 (yngE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1080 NBRP B. subtilis, Japan]
BKE18210 ([[gene|yngE]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE18210 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATAATCCATCAGCATTGCCT, downstream forward: _UP4_TAAAAGCAAGAACTTAGGAG
BKK18210 ([[gene|yngE]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK18210 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATAATCCATCAGCATTGCCT, downstream forward: _UP4_TAAAAGCAAGAACTTAGGAG