Mon Aug 31 2015 13:55:02 GMT+0200 (CEST)2025-05-23 16:57:51
title
yopL
aimP
description
unknown
Viral quorum sensor, Phage SPbeta lysogeny promoter
locus
BSU20850
BSU_20850
ec
names
yopL
aimP
AimP
yopL
outlinks
bsu
BSU20850
BSU_20850
syns
[SW|Categories] containing this gene/protein
[SW|SP-beta prophage]
Expression and Regulation
Regulation
repressed by glucose (4.2-fold) ([[protein|CcpA]]) [Pubmed|12850135], subject to carbon catabolite repression (4-fold: [[protein|CcpA]]) [Pubmed|12850135]
Expression and Regulation
Regulatory mechanism
[[protein|CcpA]]: transcription repression, [[protein|CcpA]]: transcription repression [Pubmed|12850135]
References
proteinLength
41
geneLength
126
Gene
Coordinates
2,208,855 2,208,980
The protein
Catalyzed reaction/ biological activity
Proteolytically cleaved in extracellular space to yield hexapeptide (GMPRGA) regulator. Hexapeptide re-enters cells and binds to [[protein|AimR]] to promote SPbeta lysogeny. ([Pubmed|31149347])
The protein
Paralogous protein(s)
[[this]]
The protein
Structure
Hexapeptide bound to [[protein|AimR]]: [PDB|5Y24] ([Pubmed|30224798]), [PDB|5ZW6] ([Pubmed|30323253]), [PDB|6IM4] ([Pubmed|30421358]), [PDB|6HP5] ([Pubmed|30745087]), [PDB|6JG9] ([Pubmed|31149347])
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE20850 ([[gene|aimP]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE20850 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGTCTCACCTCCTTTAA, downstream forward: _UP4_TAAAATCCATTGACACATAA
BKK20850 ([[gene|aimP]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK20850 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGTCTCACCTCCTTTAA, downstream forward: _UP4_TAAAATCCATTGACACATAA