Mon Aug 31 2015 13:57:15 GMT+0200 (CEST)2025-05-11 12:44:36
locus
BSU36700
BSU_36700
ec
outlinks
bsu
BSU36700
BSU_36700
syns
narA, narAB
[SW|Categories] containing this gene/protein
[SW|biosynthesis of cofactors]
The protein
Catalyzed reaction/ biological activity
involved in the first step of molybdenum cofactor biosynthesis (together with [[protein|YdiG]])
involved in the first step of molybdenum cofactor biosynthesis (together with [[protein|YdiG]])
AH2 + GTP + S-adenosyl-L-methionine --> (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + A + H+ + L-methionine (according to UniProt)
The protein
Protein family
MoaA family (according to Swiss-Prot)
[SW|Radical SAM superfamily] (according to UniProt)
The protein
[SW|Cofactors]
contains an iron-sulfur cluster
Fe-S cluster [pubmed|29292548]
S-adenosyl methionine (according to UniProt)
Expression and Regulation
Operon
''moaA'' [Pubmed|9353933]
References
Original publications
proteinLength
341
geneLength
1026
Gene
Coordinates
3,772,325 3,773,350
The protein
Paralogous protein(s)
[[this]]
The protein
Structure
[PDB|1TV7] (from Staphylococcus aureus, 49% identity) [pubmed|15317939]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE36700 ([[gene|moaA]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE36700 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGTAATCATAGCTACAGCCC, downstream forward: _UP4_TAATTTGAAGTCAAAAGCTT
BKK36700 ([[gene|moaA]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK36700 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGTAATCATAGCTACAGCCC, downstream forward: _UP4_TAATTTGAAGTCAAAAGCTT