SubtiBank SubtiBank
Version comparison:

Mon Aug 31 2015 13:57:15 GMT+0200 (CEST)2025-05-11 12:44:36

locus

BSU36700

BSU_36700

ec

outlinks

bsu

BSU36700

BSU_36700

syns

narA, narAB

[SW|Categories] containing this gene/protein

[SW|biosynthesis of cofactors]

The protein

Catalyzed reaction/ biological activity

involved in the first step of molybdenum cofactor biosynthesis (together with [[protein|YdiG]])

involved in the first step of molybdenum cofactor biosynthesis (together with [[protein|YdiG]])

AH2 + GTP + S-adenosyl-L-methionine --> (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + A + H+ + L-methionine (according to UniProt)

The protein

Protein family

MoaA family (according to Swiss-Prot)

[SW|Radical SAM superfamily] (according to UniProt)

The protein

[SW|Cofactors]

contains an iron-sulfur cluster

Fe-S cluster [pubmed|29292548]

S-adenosyl methionine (according to UniProt)

Expression and Regulation

Operon

''moaA'' [Pubmed|9353933]

References

Original publications

7860592, 9352926

7860592, 9352926, 15317939

proteinLength

341

geneLength

1026

Gene

Coordinates

3,772,325 3,773,350

The protein

Paralogous protein(s)

[[this]]

The protein

Structure

[PDB|1TV7] (from Staphylococcus aureus, 49% identity) [pubmed|15317939]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

BKE36700 ([[gene|moaA]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE36700 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGTAATCATAGCTACAGCCC, downstream forward: _UP4_TAATTTGAAGTCAAAAGCTT

BKK36700 ([[gene|moaA]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK36700 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGTAATCATAGCTACAGCCC, downstream forward: _UP4_TAATTTGAAGTCAAAAGCTT