2019-04-14 15:06:242025-05-10 19:40:32
locus
BSU18090
BSU_18090
outlinks
bsu
BSU18090
BSU_18090
Gene
Phenotypes of a mutant
essential [Pubmed|12682299]
essential [Pubmed|12682299]
upon overexpression, topoisomerase IV ([[protein|ParE]]-[[protein|ParC]]) can take over the functions of the type 1A topoisomerases [[protein|TopA]] and [[protein|TopB]] [pubmed|30957856]
The protein
Protein family
type II topoisomerase [[protein|GyrB]] family (together with [[protein|GyrB]]) (according to Swiss-Prot)
type II topoisomerase [[protein|GyrB]] family (together with [[protein|GyrB]]) (according to UniProt)
Biological materials
lacZ fusion
GP2550 ([[gene|parE]]::lacZ cat, based on [SW|pAC5]), available in [SW|Jörg Stülke]'s lab
GP2550 ([[gene|parE]]::lacZ cat, based on [SW|pAC5]), available in [SW|Jörg Stülke]'s lab [pubmed|30957856]
References
Original publications
The protein
Catalyzed reaction/ biological activity
ATP-dependent breakage, passage and rejoining of double-stranded DNA (according to UniProt)