2018-02-13T10:32:41.000Z2025-06-02 02:29:17
locus
BSU18090
BSU_18090
geneLength
1965
1968
outlinks
bsu
BSU18090
BSU_18090
Gene
Coordinates
1,933,477 → 1,935,444
1,933,477 1,935,444
Gene
Phenotypes of a mutant
essential [Pubmed|12682299]
essential [Pubmed|12682299]
upon overexpression, topoisomerase IV ([[protein|ParE]]-[[protein|ParC]]) can take over the functions of the type 1A topoisomerases [[protein|TopA]] and [[protein|TopB]] [pubmed|30957856]
The protein
Protein family
type IIA topoisomerase family (according to Swiss-Prot)
type II topoisomerase [[protein|GyrB]] family (together with [[protein|GyrB]]) (according to UniProt)
The protein
Paralogous protein(s)
[[protein|GyrB]]
[[this]]
References
Original publications
The protein
Catalyzed reaction/ biological activity
ATP-dependent breakage, passage and rejoining of double-stranded DNA (according to UniProt)
Biological materials
lacZ fusion
GP2550 ([[gene|parE]]::lacZ cat, based on [SW|pAC5]), available in [SW|Jörg Stülke]'s lab [pubmed|30957856]