Thu May 26 2016 12:55:02 GMT+0200 (CEST)2025-05-13 16:21:21
locus
BSU33510
BSU_33510
ec
outlinks
bsu
BSU33510
BSU_33510
[SW|Categories] containing this gene/protein
[SW|transporters/ other], [SW|trace metal homeostasis (Cu, Zn, Ni, Mn, Mo)], [SW|resistance against toxic metals]
Gene
Coordinates on the chromosome (coding sequence)
3,443,613 -> 3,443,822
The protein
[SW|Interactions]
[[protein|CopA]]-[[protein|CopZ]], for the transfer of the Cu(I) cluster [Pubmed|19751213]
Expression and Regulation
Operon
''[[protein|copZ]]-[[protein|copA]]'' [Pubmed|12779235]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|12779235]
Expression and Regulation
Regulation
induced by copper ([[protein|CsoR]]) [Pubmed|18048925,12779235]
Expression and Regulation
Regulatory mechanism
[[protein|CsoR]]: transcription repression [Pubmed|18048925]
Labs working on this gene/protein
[SW|John Helmann], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]
References
Reviews
References
Original publications
proteinLength
69
geneLength
210
Gene
Coordinates
3,443,613 3,443,822
The protein
Catalyzed reaction/ biological activity
transfers Cu(I) to [[protein|CopA]] [Pubmed|28078344]
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Domains]
HMA domain (aa 3-69) (according to UniProt)
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE33510 ([[gene|copZ]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE33510 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCAATTCCTCCTGTTT, downstream forward: _UP4_TGATTCAAGGTATCGCGCCT
BKK33510 ([[gene|copZ]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK33510 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCAATTCCTCCTGTTT, downstream forward: _UP4_TGATTCAAGGTATCGCGCCT
labs
[SW|John Helmann], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]