SubtiBank SubtiBank
Version comparison:

Thu May 26 2016 12:55:02 GMT+0200 (CEST)2025-05-13 16:21:21

locus

BSU33510

BSU_33510

ec

outlinks

bsu

BSU33510

BSU_33510

[SW|Categories] containing this gene/protein

[SW|transporters/ other], [SW|trace metal homeostasis (Cu, Zn, Ni, Mn, Mo)], [SW|resistance against toxic metals]

Gene

Coordinates on the chromosome (coding sequence)

3,443,613 -> 3,443,822

The protein

[SW|Interactions]

[[protein|CopA]]-[[protein|CopZ]], for the transfer of the Cu(I) cluster [Pubmed|19751213]

Expression and Regulation

Operon

''[[protein|copZ]]-[[protein|copA]]'' [Pubmed|12779235]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigA]] [Pubmed|12779235]

Expression and Regulation

Regulation

induced by copper ([[protein|CsoR]]) [Pubmed|18048925,12779235]

Expression and Regulation

Regulatory mechanism

[[protein|CsoR]]: transcription repression [Pubmed|18048925]

Labs working on this gene/protein

[SW|John Helmann], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]

References

Reviews

19824702

19824702, 10742187

References

Original publications

18361527, 11922674, 12590580, 14663075, 12779235, 12644235, 18048925, 19170606, 14514665, 14711369, 15212800, 19170606, 19746989, 19751213, 18419582, 22370900, 12238948, 11980486, 27197762

18361527, 11922674, 12590580, 14663075, 12779235, 12644235, 18048925, 19170606, 14514665, 14711369, 15212800, 19170606, 19746989, 19751213, 18419582, 22370900, 12238948, 11980486, 27197762, 28078344

proteinLength

69

geneLength

210

Gene

Coordinates

3,443,613 3,443,822

The protein

Catalyzed reaction/ biological activity

transfers Cu(I) to [[protein|CopA]] [Pubmed|28078344]

The protein

Paralogous protein(s)

[[this]]

The protein

[SW|Domains]

HMA domain (aa 3-69) (according to UniProt)

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

BKE33510 ([[gene|copZ]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE33510 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCAATTCCTCCTGTTT, downstream forward: _UP4_TGATTCAAGGTATCGCGCCT

BKK33510 ([[gene|copZ]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK33510 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCAATTCCTCCTGTTT, downstream forward: _UP4_TGATTCAAGGTATCGCGCCT

labs

[SW|John Helmann], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]