SubtiBank SubtiBank
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Tue Dec 13 2016 11:16:30 GMT+0100 (CET)2025-05-11 12:58:34

description

lipid II flippase, alternative to MurJ

lipid II flippase, alternative to [[protein|MurJ]]

locus

BSU04230

BSU_04230

ec

outlinks

bsu

BSU04230

BSU_04230

aminos

MHVITTQVLFIFCFLLLIHSIETLAYATRLSGARVGFIASALSLFNVMVIVSRMSNMVQQPFTGHLIDDAGKNALAIVGEQFRFLIFGSTVGTILGIILLPSFVALFSRAIIHLAGGGGSVFQVFRKGFSKQGFKNALSYLRLPSISYVKGFHMRLIPKRLFVINMLITSIYTIGVLSALYAGLLAPERSTTAVMASGLINGIATMLLAIFVDPKVSVLADDVAKGKRSYIYLKWTSVTMVTSRVAGTLLAQLMFIPGAYYIAWLTKWF

[SW|Categories] containing this gene/protein

[SW|cell wall synthesis], [SW|biosynthesis of cell wall components], [SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)], [SW|membrane proteins]

Gene

Coordinates on the chromosome (coding sequence)

474,731 -> 475,540

Gene

Phenotypes of a mutant

an ''[[protein|amj]] [[protein|murJ]]'' double mutant is not viable [Pubmed|25918422]

an ''[[gene|amj]] [[gene|murJ]]'' double mutant is not viable [Pubmed|25918422]

The protein

[SW|Localization]

cell membrane (according to Swiss-Prot)

cell membrane (according to UniProt)

Expression and Regulation

Operon

''amj'' [Pubmed|17434969]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigM]] [Pubmed|17434969]

Expression and Regulation

Regulation

induced in the stationary phase due to the internal production of toxic peptides ([SW|SdpC], [SW|SkfA]) [Pubmed|26364265]

References

Reviews

26679002

26679002, 28975672

proteinLength

269

geneLength

810

Gene

Coordinates

474,731 475,540

The protein

Protein family

Amj family (single member, according to UniProt)

The protein

Paralogous protein(s)

[[this]]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

MGNA-C089 (ydaH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2087 NBRP B. subtilis, Japan]

BKE04230 ([[gene|amj]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE04230 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGTTATTCTTCCTCCAAT, downstream forward: _UP4_TAATAAGAAAGGCTGGATCA

BKK04230 ([[gene|amj]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK04230 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGTTATTCTTCCTCCAAT, downstream forward: _UP4_TAATAAGAAAGGCTGGATCA