2017-05-09 15:36:332025-01-21 17:50:22
description
aminotransferase
N-acetyl-L,L-diaminopimelate aminotransferase
locus
BSU14000
BSU_14000
proteinLength
392
393
geneLength
1176
1182
names
patA
uat
patA
uat
dapX
outlinks
bsu
BSU14000
BSU_14000
Gene
Coordinates
1,471,857 → 1,473,038
1,471,857 1,473,038
The protein
Catalyzed reaction/ biological activity
N-acetyl-2-amino-6-ketopimelate -→ N-acetyl-L,L-2,6-diaminopimelate [Pubmed|24261876]
N-acetyl-2-amino-6-ketopimelate - N-acetyl-L,L-2,6-diaminopimelate [Pubmed|24261876]
2-oxoglutarate + N-acetyl-LL-2,6-diaminoheptanedioate --> L-2-acetamido-6-oxoheptanedioate + L-glutamate (according to UniProt)
The protein
Protein family
class-I pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)
[SW|class-I pyridoxal-phosphate-dependent aminotransferase family] (according to UniProt)
References
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Cofactors]
PLP
The protein
Structure
[PDB|1GDE] (from Pyrococcus sp., 42% identity) [pubmed|11134972]
Biological materials
Mutant
BKE14000 ([[gene|patA]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE14000 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAATTCATCACCTTAACA, downstream forward: _UP4_AACAACGGCGTTTAAGCCGT