SubtiBank SubtiBank
Version comparison:

2017-05-09 15:36:332025-01-21 17:50:22

description

aminotransferase

N-acetyl-L,L-diaminopimelate aminotransferase

locus

BSU14000

BSU_14000

proteinLength

392

393

geneLength

1176

1182

names

patA

uat

patA

uat

dapX

outlinks

bsu

BSU14000

BSU_14000

Gene

Coordinates

1,471,857 → 1,473,038

1,471,857 1,473,038

The protein

Catalyzed reaction/ biological activity

N-acetyl-2-amino-6-ketopimelate -→ N-acetyl-L,L-2,6-diaminopimelate [Pubmed|24261876]

N-acetyl-2-amino-6-ketopimelate - N-acetyl-L,L-2,6-diaminopimelate [Pubmed|24261876]

2-oxoglutarate + N-acetyl-LL-2,6-diaminoheptanedioate --> L-2-acetamido-6-oxoheptanedioate + L-glutamate (according to UniProt)

The protein

Protein family

class-I pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)

[SW|class-I pyridoxal-phosphate-dependent aminotransferase family] (according to UniProt)

References

24261876, 23109554

24261876, 23109554, 11134972, 29280348

The protein

Paralogous protein(s)

[[this]]

The protein

[SW|Cofactors]

PLP

The protein

Structure

[PDB|1GDE] (from Pyrococcus sp., 42% identity) [pubmed|11134972]

Biological materials

Mutant

BKE14000 ([[gene|patA]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE14000 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAATTCATCACCTTAACA, downstream forward: _UP4_AACAACGGCGTTTAAGCCGT