SubtiBank SubtiBank
Version comparison:

2017-8-11 16:0:32025-05-29 10:54:22

description

RNase R, required for protection against paraquat stress

RNase R, required for protection against paraquate stress

locus

BSU33610

BSU_33610

geneLength

2337

2340

ec

outlinks

bsu

BSU33610

BSU_33610

Gene

Coordinates

3,451,863 → 3,454,202

3,451,863 3,454,202

The protein

Catalyzed reaction/ biological activity

3'-5'-exoribonuclease

3'-5'-exoribonuclease

Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates (according to UniProt)

The protein

Protein family

ribonuclease II (RNB) family (according to Swiss-Prot)

RNR ribonuclease family (single member, according to UniProt)

Biological materials

Mutant

MGNA-A495 (yvaJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/495 NBRP B. subtilis, Japan]

MGNA-A495 (yvaJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/495 NBRP B. subtilis, Japan]

BKE33610 ([[gene|rnr]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE33610 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTCCATTATCCGACCTCCTG, downstream forward: _UP4_TAGCAGCTCAACCAGCAAAT

BKK33610 ([[gene|rnr]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK33610 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTCCATTATCCGACCTCCTG, downstream forward: _UP4_TAGCAGCTCAACCAGCAAAT

Labs working on this gene/protein

[SW|David Bechhofer], Mount Sinai School, New York, USA [http://www.mountsinai.org/Research/Centers%20Laboratories%20and%20Programs/Bechhofer%20Laboratory?citype=Physician&ciid=Bechhofer%20David%20H%201255565 Homepage]

References

Reviews

25878039

25878039, 30340785, 31464530

References

Original publications

15805528, 15805522, 20360175, 17369301, 23529473, 22582280

15805528, 15805522, 20360175, 17369301, 23529473, 22582280, 29873764, 29036353

The protein

Paralogous protein(s)

[[this]]

The protein

[SW|Domains]

[SW|S1 domain] (aa 628-708) (according to UniProt)

2 [SW|CSD domain]s (aa 73-133, aa 138-202) (according to the Interpro database)

The protein

Structure

[PDB|5XGU] (from E. coli, 40% identity) [pubmed|29036353]

labs

[SW|David Bechhofer], Mount Sinai School, New York, USA [http://www.mountsinai.org/Research/Centers%20Laboratories%20and%20Programs/Bechhofer%20Laboratory?citype=Physician&ciid=Bechhofer%20David%20H%201255565 Homepage]