2018-11-23 15:40:312025-07-10 21:35:17
locus
BSU22070
BSU_22070
geneLength
582
585
outlinks
bsu
BSU22070
BSU_22070
Gene
Coordinates
2,319,440 → 2,320,024
2,319,440 2,320,024
The protein
Catalyzed reaction/ biological activity
XMP diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate xanthine (according to Swiss-Prot)
5-phospho-α-D-ribose 1-diphosphate + xanthine --> diphosphate + XMP (according to UniProt)
The protein
[SW|Localization]
cell membrane (according to Swiss-Prot)
cytoplasm (according to Swiss-Prot)
Biological materials
Mutant
MGNA-A870 (xpt::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/870 NBRP B. subtilis, Japan]
BKE22070 (Δ[[gene|xpt]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE22070 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCCTGTCTACCTCCGTTA, downstream forward: _UP4_TCCTTCGTACAGGAGGTTCA
BKK22070 (Δ[[gene|xpt]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK22070 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCCTGTCTACCTCCGTTA, downstream forward: _UP4_TCCTTCGTACAGGAGGTTCA
MGNA-A870 (xpt::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/870 NBRP B. subtilis, Japan]
BKE22070 ([[gene|xpt]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE22070 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCCTGTCTACCTCCGTTA, downstream forward: _UP4_TCCTTCGTACAGGAGGTTCA
BKK22070 ([[gene|xpt]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK22070 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCCTGTCTACCTCCGTTA, downstream forward: _UP4_TCCTTCGTACAGGAGGTTCA
References
The protein
Protein family
[SW|Purine/pyrimidine phosphoribosyltransferase family] (according to UniProt)
The protein
Paralogous protein(s)
[[this]]
The protein
Effectors of protein activity
strongly inhibited by pGpp and ppGpp [pubmed|32446804]
weakly inhibited by pppGpp [pubmed|32446804]