SubtiBank SubtiBank
Version comparison:

2018-11-23 15:40:312025-07-10 21:35:17

locus

BSU22070

BSU_22070

geneLength

582

585

outlinks

bsu

BSU22070

BSU_22070

Gene

Coordinates

2,319,440 → 2,320,024

2,319,440 2,320,024

The protein

Catalyzed reaction/ biological activity

XMP diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate xanthine (according to Swiss-Prot)

5-phospho-α-D-ribose 1-diphosphate + xanthine --> diphosphate + XMP (according to UniProt)

The protein

[SW|Localization]

cell membrane (according to Swiss-Prot)

cytoplasm (according to Swiss-Prot)

Biological materials

Mutant

MGNA-A870 (xpt::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/870 NBRP B. subtilis, Japan]

BKE22070 (Δ[[gene|xpt]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE22070 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCCTGTCTACCTCCGTTA, downstream forward: _UP4_TCCTTCGTACAGGAGGTTCA

BKK22070 (Δ[[gene|xpt]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK22070 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCCTGTCTACCTCCGTTA, downstream forward: _UP4_TCCTTCGTACAGGAGGTTCA

MGNA-A870 (xpt::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/870 NBRP B. subtilis, Japan]

BKE22070 ([[gene|xpt]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE22070 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCCTGTCTACCTCCGTTA, downstream forward: _UP4_TCCTTCGTACAGGAGGTTCA

BKK22070 ([[gene|xpt]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK22070 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCCTGTCTACCTCCGTTA, downstream forward: _UP4_TCCTTCGTACAGGAGGTTCA

References

16716072, 9098051, 12923093, 15629952, 11591660, 15610857, 20200045, 11591660, 20204714, 26704707, 27941758, 28541183, 28798404

16716072, 9098051, 12923093, 15629952, 11591660, 15610857, 20200045, 11591660, 20204714, 26704707, 27941758, 28541183, 28798404, 32446804

The protein

Protein family

[SW|Purine/pyrimidine phosphoribosyltransferase family] (according to UniProt)

The protein

Paralogous protein(s)

[[this]]

The protein

Effectors of protein activity

strongly inhibited by pGpp and ppGpp [pubmed|32446804]

weakly inhibited by pppGpp [pubmed|32446804]