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yxeN [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]
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yxeN [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

putative cysteine ABC transporter (permease), the yxeK-snaB-yxeM-yxeN-yxeO-sndB-yxeQ operon may be implicated in the utilization of a modified cysteine variant
locus
BSU39490
pI
9.48
mw
24.00 kDa
function
uptake of cysteine
product
putative cysteine ABC transporter (permease)
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.2|Uptake of amino acids]
  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.9|Biosynthesis/ acquisition of cysteine]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.4|Sulfur metabolism] → [category|SW 2.6.4.3|Conversion of S-(2-succino)cysteine to cysteine]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|ABC transporters], [SW|biosynthesis/ acquisition of amino acids], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|CymR regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    4,058,791 -> 4,059,465

    The protein

    Protein family

  • binding-protein-dependent transport system permease family (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''[protein|search|yxeK]-[protein|search|snaB]-[protein|search|yxeM]-[protein|search|yxeN]-[protein|search|yxeO]-[protein|search|sndB]-[protein|search|yxeQ]'' [Pubmed|10746760]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|16513748]
  • Regulation

  • repressed in the presence of cysteine ([protein|search|CymR]) [Pubmed|16513748]
  • Regulatory mechanism

  • [protein|search|CymR]: transcription repression [Pubmed|16513748]
  • Biological materials

    Mutant

  • 1A950 ( ''yxeN''::''cat''), [Pubmed|15262924], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A950&Search=1A950 BGSC]
  • References

  • 10746760,10092453,16513748,18763711