cimH [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

transporter for citrate (proton symport)

locus: BSU38770

pI: 6.55

mw: 48.00 kDa

function: citrate uptake

product: transporter for citrate (proton symport)

essential: no

synonyms: yxkJ

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.4|Transporter for organic acids]
• [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.1|Utilization of organic acids]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|transporters/ other], [SW|utilization of specific carbon sources], [SW|membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|CcpA regulon]

Gene

Coordinates on the chromosome (coding sequence): 3,979,753 -> 3,981,105

The protein

Catalyzed reaction/ biological activity

• uptake of citrate (symport with protons) [Pubmed|11566984]

Protein family

• sodium:citrate (SCF) symporter family (according to Swiss-Prot) 2-hydroxycarboxylate transporter family

Paralogous protein(s)

• [protein|search|MaeN]

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|cimH]'' [Pubmed|21815947]

Regulation

• repressed by glucose ([protein|search|CcpA]) [Pubmed|10666464]

Regulatory mechanism

• [protein|search|CcpA]: transcription repression [Pubmed|10666464]

Additional information

• the mRNA is substantially stabilized upon depletion of [Rny|search|RNase Y] [PubMed|21815947]

References

Reviews

• 16339740

Original publications

• 12525174,10666464,11566984,21815947