spoVC [Mon Jan 18 2016 18:56:54 GMT+0100 (CET)]

general stress protein, peptidyl-tRNA hydrolase

locus: BSU00530

pI: 5.00

mw: 20.00 kDa

function: spore coat formation

product: peptidyl-tRNA hydrolase

essential: yes

ec: 3.1.1.29

synonyms: pth

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.12|Translation/ other]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

[SW|Categories] containing this gene/protein

• [SW|translation], [SW|general stress proteins (controlled by SigB)], [SW|essential genes], [SW|sporulation proteins]

This gene is a member of the following [SW|regulons]

• [SW|SigB regulon]

Gene

Coordinates on the chromosome (coding sequence): 59,504 -> 60,070

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

Catalyzed reaction/ biological activity

• N-substituted aminoacyl-tRNA H₂O = N-substituted amino acid tRNA (according to Swiss-Prot)

Protein family

• PTH family (according to Swiss-Prot)

Structure

• [PDB|4QT4] (from ''Streptococcus pyogenes'', 48% identity)

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

[SW|Sigma factor]

• [protein|search|SigB] [Pubmed|11544224]

Regulation

• induced by stress ([protein|search|SigB]) [Pubmed|11544224]

References

• 11544224,12100553