comQ

prenylation of comX and surfactin expression (srfA)

Locus: BSU_31710

Isoelectric point: 4.89

Molecular weight: 34.05 kDa

Protein length: 299 aa

Gene length: 900 bp

Function: regulation of quorum sensing

Product: prenyltransferase

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Information processing → Genetics → Genetic competence
• Information processing → Protein synthesis, modification and degradation → Protein modification → Protein modification/ other
• Information processing → Regulation of gene expression → Quorum sensing
• Lifestyles → Exponential and early post-exponential lifestyles → Genetic competence
• Groups of genes → Membrane proteins

Gene

Coordinates: 3,256,008 → 3,256,907

Phenotypes of a mutant

• the mutation suppresses the mucoid phenotype of motA or motB mutants due to loss of DegU phosphorylation and concomitant reduced expression of the capB-capC-capA-capE operon PubMed

The protein

Catalyzed reaction/ biological activity

• prenylation of ComX on W-53 PubMed

Localization

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• Genes: comQ-comX-comP-comA-yuxO
  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

Biological materials

Mutant

• BKE31710 (ΔcomQ::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTTTCTCCTTGATCCGGA, downstream forward: _UP4_AGTTATACAAAGGGGGATAC
• BKK31710 (ΔcomQ::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTTTCTCCTTGATCCGGA, downstream forward: _UP4_AGTTATACAAAGGGGGATAC

References

Reviews

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Original publications

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