glyQ

glycyl-tRNA synthetase (alpha subunit)

Locus: BSU_25270

Isoelectric point: 4.80

Molecular weight: 33.83 kDa

Protein length: 295 aa

Gene length: 888 bp

Function: translation

Product: glycyl-tRNA synthetase (alpha subunit)

Essential: yes

E.C.: 6.1.1.14

Synonyms: yqfJ

Genomic Context

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Categories containing this gene/protein

• Information processing → Protein synthesis, modification and degradation → Translation → Aminoacyl-tRNA synthetases
• Groups of genes → Essential genes

Gene

Coordinates: 2,607,762 → 2,608,649

Phenotypes of a mutant

• essential PubMed

The protein

Catalyzed reaction/ biological activity

• ATP + glycine + tRNA^Gly --> AMP + diphosphate + glycyl-tRNA^Gly (according to UniProt)

Protein family

• Class-II aminoacyl-tRNA synthetase family (according to UniProt)

Structure

• 1J5W (from Thermotoga maritima, 55% identity, 72% similarity)
• 6POM (the glyQ riboswitch in complex with tRNA-Gly) PubMed

Localization

• cytoplasm (according to Swiss-Prot)

Additional information

• belongs to the 100 most abundant proteins PubMed

Expression and Regulation

Operons

• Genes: glyQ-glyS
  Description: PubMed

  Regulatory mechanism

  • T-box: anti-termination, PubMed, in T-box

  Regulation

  • induced by glycine limitation (T-box) PubMed

References

Reviews

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The glyQ riboswitch

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Other publications

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