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ykcC
similar to lipoteichoic acid glycosyltransferase
function
decoration of lipoteichoic acid with galactose residues
Genomic Context
categories
[category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]Gene
Coordinates
1,356,447 → 1,357,418
The protein
Protein family
[SW|glycosyltransferase 2 family] (according to UniProt)Paralogous protein(s)
[protein|824E6AE2FFA3CBC9F90648F15178A00A6CC49E4C|CsbB][protein|EF18470AD2B07755431534B52A8FCE6754FDBA9D|YkoT]: Structure
[PDB|5EKP] (from Synechocystis sp., 47% identity) [pubmed|26729507][SW|Localization]
cell membrane (heterogeneous) [Pubmed|16479537]Expression and Regulation
Operons
genes
[gene|7039FCF49F97FFEF37ED48D6F860E3873A5CF308|ykcB]-[gene|FD76A781162795EAF174B59C0A90D2ED3ACC0AB7|ykcC]
description
[Pubmed|18175906]
regulatory mechanism
[protein|706983E6942E883D3A9D45693E7B4015AEABE60B|YclJ]: activation, [Pubmed|20512483], in [regulon|706983E6942E883D3A9D45693E7B4015AEABE60B|YclJ regulon][protein|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|YrkP]: activation, [Pubmed|18175906], in [regulon|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|YrkP regulon]view in new tabBiological materials
Mutant
MGNA-A739 (ykcC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/739 NBRP B. subtilis, Japan]BKE12890 (Δ[gene|FD76A781162795EAF174B59C0A90D2ED3ACC0AB7|ykcC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE12890 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATGTCTGCTCATGTTTTTGC, downstream forward: _UP4_TAACCTCAAACCCCCTGTCCBKK12890 (Δ[gene|FD76A781162795EAF174B59C0A90D2ED3ACC0AB7|ykcC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK12890 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATGTCTGCTCATGTTTTTGC, downstream forward: _UP4_TAACCTCAAACCCCCTGTCCReferences
20512483,18175906,16479537,21630458,27185829,26729507