gtcA [2019-04-22 18:57:17]

teichoic acid glycosylation protein

locus: BSU38210

pI: 8.50

mw: 14.21 kDa

protein length: 127 aa

gene length: 384 bp

function: biosynthesis of teichoic acids

product: teichoic acid glycosylation protein

essential: no

synonyms: ywcD, ipa-34d,gtaC

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.4|Biosynthesis of teichoic acid]
• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.3|Biosynthesis of teichoic acid]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 3,921,891 → 3,922,274

The protein

Protein family

• gtrA family (according to Swiss-Prot)

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operons

• genes: [gene|C3D87DAA8DB124D50D2C2B2D424C9608C0DE067F|ywcC]-[gene|FD30C4E458E63E8D6A932B351D4224F1AACD4B1B|gtcA]-[gene|36930CC6FDFCA23D43E264FEA375B78A1434E1BD|galK]-[gene|591428EA1C3D40322BB942429607AF61A90BAF41|galT]
  description: [Pubmed|22383849,22893383]

  regulation

  • repressed by glucose ([protein|search|CcpA]) [Pubmed|10666464]

Biological materials

Mutant

• MGNA-B231 (ywcD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1230 NBRP B. subtilis, Japan]
• BKE38210 (Δ[gene|FD30C4E458E63E8D6A932B351D4224F1AACD4B1B|gtcA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE38210 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAATTATTTCTCTATACT, downstream forward: _UP4_TGAGAGGACTGCAGCATATG
• BKK38210 (Δ[gene|FD30C4E458E63E8D6A932B351D4224F1AACD4B1B|gtcA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK38210 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAATTATTTCTCTATACT, downstream forward: _UP4_TGAGAGGACTGCAGCATATG

References

• 22383849,22893383